Dr. Ian Justl Ellis and Recess Fitness Club are proud to offer tools to help YOU achieve a healthy, fit body for life:
- GLP-1 Weight Loss Meds
- Hormone Replacement
- Peptide Treatments
- Low-Cost Lab Testing
- 24/7 Physician Access
- And Much More!
Sign up for any Recess Rx membership to save 50% on all medications and services.
Dr. Ian Justl Ellis and Recess Fitness Club are proud to offer tools to help YOU achieve a healthy, fit body for life:
- GLP-1 Weight Loss Meds
- Hormone Replacement
- Peptide Treatments
- Low-Cost Lab Testing
- 24/7 Physician Access
- And Much More!
Sign up for a Recess Rx membership to save 50% on all medications & services.
Dr. Ian Justl Ellis and Recess Fitness Club are proud to offer tools to help YOU achieve a healthy, fit body for life:
- GLP-1 Weight Loss Meds
- Hormone Replacement
- Peptide Treatments
- Low-Cost Lab Testing
- 24/7 Physician Access
- And Much More!
Sign up for any Recess Rx membership to save 50% on medications & services.
SERVICES
GLP-1 WEIGHT LOSS
GLP-1 weight loss treatments allow nearly anyone to reach a healthy weight, starting at $249 per month.
HORMONE THERAPY
Reversing low energy, low libido, and other signs of aging in men and women starts at $149 per month.
PEPTIDE THERAPY
Peptide treatments can speed recovery, reduce inflammation, improve brain function, and more.
WALK-IN LABS
Take an inside look at your health with our convenient walk-in lab testing. Physician review is included.
DOC ON DEMAND
Access board-certified M.D. care when YOU need it. Text Dr. Justl Ellis anytime at (817) 583-8542.
AND MUCH MORE!
We offer a full menu of health and wellness treatments ranging from low HGH therapy to hair loss care.
SERVICES
GLP-1 WEIGHT LOSS
GLP-1 weight loss treatments allow nearly anyone to reach a healthy weight, starting at $249 per month.
HORMONE THERAPY
Reversing low energy, low libido, and other signs of aging in men and women starts at $149 per month.
PEPTIDE THERAPY
Peptide treatments can speed recovery, reduce inflammation, improve brain function, and more.
WALK-IN LABS
Take an inside look at your health with our convenient walk-in lab testing. Physician review is included.
DOC ON DEMAND
Access board-certified M.D. care when YOU need it. Text Dr. Justl Ellis anytime at (817) 583-8542.
AND MUCH MORE!
We offer a full menu of health and wellness treatments ranging from low HGH therapy to hair loss care.
memberships
memberships
Recess Rx membership is required for GLP-1 and HRT treatments and optional for all other medications and services. Members receive 50% off all orders.
GLP-1 Membership
$239.00 per month
+ medication cost
INCLUDES:
- Semaglutide or tirzepatide weight loss medication
- Weekly dose titration and on-demand physician access
- 50% off all Recess Rx medications and services
EFFICACY:
- Semaglutide: lose 16%+ body weight
- Tirzepatide: lose 23%+ body weight
NOTES:
- 3-month minimum commitment
- Click here for total cost of treatment
HRT Membership
$149.00 per month
+ medication cost
INCLUDES:
- Customized hormone replacement therapy
- Lab checks four times a year
- 50% off all Recess Rx medications and services
NOTES:
- Male and female regimens available
- 3-month minimum commitment
- Click here for full pricing details
Elite Rx Membership
$99.00 per month
INCLUDES:
- 50% off all Recess Rx medications and services other than GLP-1 and HRT medications*
NOTES:
- *Patients needing GLP-1 or HRT treatment must purchase that membership instead
- 2-month minimum commitment
medications
medications
A free consultation is required to obtain your first prescription. Sign up for any Recess Rx membership to save 50% on all prescriptions.
GLP-1 MEMBER MEDS
GLP-1 PEPTIDES
- Semaglutide + NAD
- Lose ~16% body weight while improving metabolism and energy production.
- Semaglutide + B6
- Lose ~16% body weight while enhancing metabolism and decreasing nausea.
- Semaglutide + B6 (Oral)
- Oral combination that regulates appetite and enhances metabolism.
GLP-1/GIP PEPTIDES
- Tirzepatide + Levocarnitine
- Lose ~23% body weight while helping reduce muscle loss.
- Tirzepatide + B6
- Lose ~23% body weight while improving metabolism and decreasing nausea.
HRT MEMBER MEDS
DIRECT REPLACEMENT
- Bi-Test (Cypionate + Propionate)
- Combination to treat low testosterone and promote muscle growth.
- Nandrolone Decoanate
- Injectable anabolic steroid used to treat muscle wasting conditions.
- Testosterone Troches
- Oral treatment to improve symptoms like fatigue and reduced libido.
- Testosterone Cream
- Topical testosterone used to improve mood, libido, and muscle mass.
- Testosterone Cypionate
- Injectable long-acting testosterone used to treat low testosterone levels.
- Testosterone + Anastrozole
- Aromatase inhibitor addition reduces estrogen-related side effects.
- Testosterone + Nandrolone
- Two steroid combo used to treat low testosterone and muscle loss.
OTHER THERAPIES
- Clomiphene + Resveratrol + B6 + ZMA
- Stimulates testosterone production while supporting energy levels.
- Enclomiphene
- Treats low testosterone by stimulating natural testosterone production.
- Gonadorelin
- Gonadotropin-releasing hormone which stimulates testosterone production.
- Kisspeptin-10
- Increases testosterone and fertility by stimulating the release of GnRH.
- Oxandrolone
- Synthetic analog of testosterone which can decrease muscle loss.
INJECTABLE
- Testosterone Cypionate
- Injectable long-acting testosterone used to treat low testosterone levels.
- Kisspeptin-10
- Increases testosterone and fertility by stimulating the release of GnRH.
ORAL
- DHEA Capsules
- Oral hormone that supports hormone balance, energy, and overall well-being.
- DHEA + Pregnenolone Capsules
- Oral combination used to support hormone balance and cognitive function.
- Progesterone Tablets + Troches
- Hormone used to balance estrogen and protect the uterine lining.
- Testosterone Tablets + Troches
- Oral hormone used to improve symptoms like fatigue and reduced libido.
TOPICAL
- Bi-Estrogen Cream
- Topically applied HRT combining two forms of estrogen.
- Bi-Estrogen + Progesterone + Testosterone Cream
- Topically applied HRT that addresses multiple menopausal symptoms.
- Estradiol Cream
- Potent topical estrogen used in HRT to alleviate menopausal symptoms.
- Estriol Cream
- Topically applied estrogen used in HRT for its favorable safety profile.
- Progesterone Cream
- Hormone used to balance estrogen and protect the uterine lining.
- Testosterone Cream
- Topical formulation used to improve mood, libido, and muscle mass.
VAGINAL
- Progesterone Vaginal Suppository
- Hormone used to balance estrogen and protect the uterine lining.
OTHER MEDICATIONS
PEPTIDES
- FOXO4-DRI
- Promotes healthy aging and potentially reduces age-related damage.
- MOTS-C
- Regulates metabolism and enhances cellular energy production.
- SS-31 (Elamipretide)
- Reduces oxidative stress and improve mitochondrial function.
- Dihexa
- Peptide which may enhance cognitive and nerve function.
- Selank (TP-7)
- Peptide which may reduce anxiety and improve cognitive function.
- Semax
- Peptide which may improve brain function and neurological injury recovery.
- GHK-Cu
- Peptide used for its skin healing, anti-aging, and regenerative properties.
- GHK-Cu + Biotin Scalp Foam
- Topical combination which enhances hair growth and skin health.
OTHER
- Bimatoprost
- Topical solution used to promote eyelash growth.
- Finasteride + Biotin + Vitamin C
- Oral combination used to treat hair loss and support hair health.
- Minoxidil + Finasteride
- Topical solution combining multiple synergistic medications to treat hair loss.
- Minoxidil + Finasteride + Retinoic Acid + Fluocinolone
- Topical solution combining multiple synergistic medications to treat hair loss.
PEPTIDES
- CJC-1295
- Growth hormone-releasing hormone analog that increases HGH levels.
- Ibutamoren (MK-677)
- HGH secretagogue that mimics ghrelin, increasing HGH levels.
- Ipamorelin
- Stimulates HGH release, aiding in muscle growth and fat loss.
- Sermorelin
- Growth hormone-releasing peptide which stimulates HGH production.
- Ipamorelin + CJC-1295
- Combination which enhances HGH secretion for muscle growth and anti-aging.
- Ipamorelin + Sermorelin
- Combination which stimulates HGH release for muscle growth and anti-aging.
- Ipamorelin + Tesamorelin
- Combination which increases HGH levels, promoting fat loss and muscle growth.
PEPTIDES
- Melanotan II
- Peptide used to enhance skin pigmentation and support the immune system.
- LL-37
- Antimicrobial peptide that supports wound healing and immune response.
- Thymosin Alpha-1
- Enhances immune function and supports defense against infections and diseases.
ERECTILE DYSFUNCTION
- Sildenafil (Viagra)
- Short-acting erectile dysfunction treatment to increase penile blood flow.
- Tadalafil (Cialis)
- Long-acting erectile dysfunction treatment to increase penile blood flow.
LIBIDO
- Oxytocin
- Hormone which promotes social bonding and enhances sexual arousal.
- PT-141 (Bremelanotide)
- Peptide which activates receptors involved in sexual arousal.
- Tadalafil + PT-141 + Oxytocin
- Treats erectile dysfunction while enhancing sexual arousal and intimacy.
- GHK-Cu
- Injectable peptide with skin healing, anti-aging, and regenerative properties.
- GHK-Cu + Biotin Topical Foam
- Topical combination used to enhance hair growth and skin health.
- LL-37
- Antimicrobial peptide that supports wound healing and the immune response.
- Melanotan II
- Enhances skin pigmentation and supports the immune system.
PEPTIDES
- DSIP (Delta Sleep Inducing Peptide)
- Peptide that offers potential benefits for insomnia and other sleep disorders.
- Ibutamoren (MK-677)
- Growth hormone secretagogue that increases both deep and REM sleep.
- BPC-157
- Repairs tissues, reduces inflammation, and accelerates injury recovery.
- BPC-157 + Thymosin Beta-4
- Combination reduces inflammation and accelerates injury recovery.
- Thymosin Beta-4
- Promotes healing by enhancing cell migration and reducing inflammation.
INJECTABLES
- Ascorbic Acid (Vitamin C)
- Antioxidant which boosts the immune system and supports skin health.
- B-Complex + Lidocaine + Methylfolate
- B vitamin combination to support nerve health and relieve pain.
- B-Complex + Methyl B12
- B vitamin combination which supports energy production and nerve health.
- Glutathione
- Supports the immune system and protects from oxidative damage.
- Methycobalamin (B12)
- Supports nerve health, blood production, and energy metabolism.
- NAD+
- Coenzyme involved in energy production, DNA repair, and metabolic health.
- Pyridoxine (B6)
- Supports nerve function, amino acid metabolism, and blood production.
- Vitamin D3
- Supports bone health, immune function, and calcium absorption.
lab panels
lab panels
Walk in to any LabCorp to get your blood drawn. No appointment is needed. Results will be sent to directly to you. Book a free consultation to have your results interpreted. Recess Rx members save 50%.
$384.50 (Member Price)
$769.00 (Non-Member Price)
Our flagship lab panel measures over 68 biomarkers and provides a truly comprehensive look at your body’s health and function.
SEX HORMONES
- Testosterone (Free, Total w/SHBG)
- DHEA-Sulfate
- Estradiol (E2)
- Follicle-Stimulating Hormone (FSH) (Females)
- Progesterone (Females)
THYROID
- T3 (Free)
- T3 (Reverse)
- T4 (Free)
- Thyroid Stimulating Hormone (TSH)
- Thyroid Peroxidase Antibodies
CARDIOVASCULAR
- Complete Blood Count (CBC)
- Cortisol
- Total Cholesterol
- High-Density Lipoprotein (HDL)
- Low-Density Lipoprotein (LDL)
- Triglycerides
- ApoB
- Ferritin
- HsCRP
- Lipo(a)
BLOOD SUGAR
- Glucose
- Hemoglobin A1C
- Insulin
METABOLIC AND LIVER
- Complete Metabolic Panel (CMP)
- Magnesium
- ALT
- AST
VITAMINS
- Folate
- Vitamin D, 25-OH (Total)
- Vitamin B-12
PROSTATE HEALTH
- Prostate Specific Antigen, Total (Males)
$64.50 (Member Price)
$129.00 (Non-Member Price)
Our General Wellness Panel is an excellent choice for patients wishing to take an affordable look at their overall metabolic and cardiovascular health.
INCLUDES:
- Complete Blood Count (CBC)
- Complete Metabolic Panel (CMP)
- Hemoglobin A1C
- Lipid Panel
- Thyroid Stimulating Hormone
- Vitamin D, 25-OH, Total
$64.50 (Member Price)
$129.00 (Non-Member Price)
Our Weight Loss Panel takes a focused look at important biomarkers related to obesity and overweight, including glucose metabolism, cardiovascular risk, and thyroid function.
INCLUDES:
- Complete Blood Count (CBC)
- Complete Metabolic Panel (CMP)
- Lipid Panel
- Hemoglobin A1C
- Insulin, Fasting
- T3 (Free)
- T4 (Total)
- Thyroid Stimulating Hormone (TSH)
$139.50 (Member Price)
$279.00 (Non-Member Price)
Our Men’s Hormone Panel takes a comprehensive look at biomarkers related to male hormone system function. It also includes screening tests to assess for prostate cancer risk and thyroid disease.
INCLUDES:
- Complete Blood Count (CBC)
- Complete Metabolic Panel (CMP)
- Cortisol
- Estradiol (E2)
- Follicle Stimulating Hormone
- Lipid Panel
- Luteinizing Hormone
- Prostate Specific Antigen (Total)
- Testosterone (Free, Total w/SHBG)
- T3 (Free)
- T4 (Total)
- Thyroid Peroxidase Antibodies
- Thyroid Stimulating Hormone
- Vitamin B-12
- Vitamin D, 25-OH, Total
$139.50 (Member Price)
$279.00 (Non-Member Price)
Our Women Hormone Panel takes a comprehensive look at biomarkers related to female hormone system function. It also includes screening tests to assess for thyroid disease.
INCLUDES:
- Complete Blood Count (CBC)
- Complete Metabolic Panel (CMP)
- Cortisol
- Estradiol (E2)
- Follicle Stimulating Hormone (FSH)
- Lipid Panel
- Luteinizing Hormone (LH)
- Progesterone
- Testosterone (Free, Total w/SHBG)
- T3 (Free)
- T4 (Total)
- Thyroid Stimulating Hormone (TSH)
- Thyroid Peroxidase Antibodies
- Vitamin B-12
- Vitamin D, 25-OH, Total
$139.50 (Member Price)
$279.00 (Non-Member Price)
Our Thyroid Panel takes a complete look at your thyroid health, including reverse T3 testing as well as screening for Hashimoto’s thyroiditis.
If you only need basic thyroid testing without RT3 and Hashimoto’s screening, consider purchasing one of our cheaper lab panels that includes these tests.
INCLUDES:
- T3 (Free)
- T3 (Reverse)
- T4 (Free)
- Thyroid Stimulating Hormone (TSH)
- Thyroglobulin Autoantibodies
- Thyroid Peroxidase Antibodies
$299.00 (Non-Member Price)
Our Peptide Panel evaluates labs relevant to peptide treatment, with a special focus on testing related to growth hormone modulating peptides such as sermorelin and ipamorelin.
INCLUDES:
- Complete Blood Count (CBC)
- Comprehensive Metabolic Panel (CMP)
- Prolactin
- Thyroid Stimulating Hormone
- Insulin Growth Factor 1 (IGF-1)
- Hemoglobin A1C
- C-Peptide
$99.50 (Member Price)
$199.00 (Non-Member Price)
Our Fatigue Panel evaluates for reversible causes of fatigue, including iron deficiency anemia, vitamin deficiencies, and hormonal or thyroid dysfunction.
INCLUDES:
- Complete Blood Count (CBC)
- Comprehensive Metabolic Panel (CMP)
- Estradiol (E2)
- Ferritin
- Iron Total Binding Capacity
- T3 (Total)
- T4 (Total)
- Thyroid Stimulating Hormone
- Testosterone (Total)
- Vitamin B-12
- Vitamin D, 25-OH, Total
$84.50 (Member Price)
$169.00 (Non-Member Price)
Our Heart Health Panel measures specific lipids, lipoproteins, and inflammatory markers that are known predictors of cardiovascular disease. Results may be used to assess a patient’s overall cardiovascular risk.
INCLUDES:
- Lipid Panel
- C-Reactive Protein (CRP)
- NMR LipoProfile
- Lipoprotein(a)
Have specific lab testing needs in mind that aren’t satisfied by the standard lab panels, or want to combine elements from several panels into a single discounted panel?
Click here to access an selection form from which you may create your own custom lab panel from hundreds of available tests. Simply click the checkbox next to each test you desire and submit the form.
Alternatively, you may simply text your desired list of lab tests directly to Dr. Justl Ellis at (817) 583-8542.
After receiving your lab test list, Dr. Justl Ellis will send you a quote.
Once you approve the quote, you will receive an e-mail with a custom lab requisition that may be redeemed by “walking in” to any LabCorp facility during business hours.
MEET THE DOC
Dr. Ian Justl Ellis is a board-certified physician with a doctorate from the University of Colorado School of Medicine. He completed a residency in Emergency Medicine and is fellowship-trained in Medical Education. He graduated summa cum laude with an undergraduate major in Athletic Training.
He is also a Personal Fitness Instructor and nutrition expert certified by the International Fitness Professionals Association and has helped clients of all ages and fitness levels achieve their goals since early in his college career.
He founded Recess Rx to provide patients with life-changing medical care while simultaneously helping improve patients’ diet, exercise, and lifestyle choices. His goal is for every patient to achieve and maintain a healthy, fit body — for life!
Have questions? Dr. Justl Ellis may be contacted directly via text message at (817) 583-8542 or via email at md@recessrx.com.
wall of fame
Victoria E.
Tiffany M.
Sharon H.
Robert M.
Nicholas E.
Marcia S.
Angelica G.
Victoria E.
Tiffany M.
Sharon H.
Robert M.
Nicholas E.
Marcia S.
Angelica G.
GLP-1 FAQ
Patients on semaglutide lose an average of 16% of their weight, and patients on tirzepatide lose an average of 22.5% of their weight. NEJM 2022 and Nat Med 2022
Patients taking semaglutide and tirzepatide lose an average of 16% and 22.5% of their body weight. NEJM and Nat Med 2022
GLP-1 agonist medications are a genuinely revolutionary class of medications that put achieving a healthy body weight within reach for most people.
The most well known of these medications, and the most affordable, is semaglutide (commercially sold under the brand names Ozempic® and Wegovy®).
A second-generation medication called tirzepatide (brand name Mounjaro®) is also available. This medication binds to an additional receptor called the glucose-dependent insulinoptropic polypeptide (GIP), intensifying its treatment effect.
GLP-1 (glucagon-like-peptide 1) is an endogenous peptide naturally found in the pancreas, peripheral and central nervous system, heart and blood vessels, kidneys, lungs, and intestinal mucosa.
Both semaglutide and tirzepatide are stabilized peptides that bind tightly to the GLP-1 hormone receptor.
Stimulation of the GLP-1 receptor has has many beneficial effects, but primary among them is extremely potent appetite suppression and dramatic slowing of emptying of the stomach—eliminating cravings and causing a rapid reduction in body weight.
Tirzepatide is a second generation medication which binds to an additional receptor called the glucose-dependent insulinotropic polypeptide (GIP) receptor. This dual-receptor action results in even more dramatic results.
Semaglutide:
An average patient taking semaglutide will lose 16% of their body weight—nearly 7x more than with lifestyle interventions alone.
Put another way, the average 200 pound patient can expect to lose at least 30-35 pounds or more during a course of treatment.
Tirzepatide:
An average patient taking tirzepatide will lose a remarkable 22.5% of their body weight—nearly 10x more than with lifestyle interventions alone.
The average 200 pound patient could expect to lose at least 45 pounds or more during a course of these medications.
Additional treatment effects:
Patients taking GLP-1 agonists also show dramatic improvements in waist circumference, blood sugar and blood pressure levels, sleep apnea, and overall level of physical function—as well as a significant reduction in risk of adverse cardiac events such as heart attack and stroke.
Side effects of GLP-1 medications are generally mild, and most can be decreased or eliminated by careful adjustment of your diet under the supervision of Dr. Justl Ellis.
The most commonly experienced side effects are nausea and diarrhea. Occasionally, moderately severe side effects such as stomach pain and vomiting may occur.
Very severe or life-threatening side effects are very rare but can occur.
Our formulations of both semaglutide and tirzepatide are compounded with either pyridoxine (which helps decrease unwanted gastrointestinal side effects such as nausea), NAD+ (which helps with metabolic regulation and energy production), or levocarnitine (which helps mitigate muscle loss).
Comprehensive information on GLP-1 medications written for patients, including efficacy data, contraindications, and a full list of potential side effects, may be accessed via this document from the Department of Texas Health and Services.
FDA prescriber information data sheets for semaglutide may be accessed here.
FDA prescriber information data sheets for tirzepatide may be accessed here.
Semaglutide and tirzepatide are both administered via subcutaneous injection (under the skin) once a week.
A syringe kit with complete instructions of how to draw up and self-administer the medication will be shipped to you with your first medication delivery.
Yes!
We ship compounded semaglutide and tirzepatide directly to your door from our pharmacy partners at a fraction of the cost of “brand name” medications.
Semaglutide is the more affordable of the two options. Many patients recoup the entire cost of semaglutide treatment via lower food costs alone!
Tirzepatide is a premium option and is available to those wishing to spend more for the best possible results.
You may use Health Savings Account (HSA) funds to pay for Recess Rx services.
Comprehensive information on GLP-1 medications written for patients, including efficacy data, contraindications, and potential side effects, may be accessed via this document from the Department of Texas Health and Services.
FDA prescriber information data sheets for semaglutide may be accessed here.
FDA prescriber information data sheets for tirzepatide may be accessed here.
Treatment effects for semaglutide were first described in this 2021 study in the New England Journal of Medicine. These findings were confirmed in the STEP 5 Trial published in Nature Medicine in 2022.
Treatment effects for tirzepatide were first described in this 2022 study, also published in the New England Journal of Medicine.
Multiple trials showing reduction in risk of adverse cardiac events such as heart attack in patients taking GLP-1 agonist medication may be reviewed here and here.
Further resources are available on request.
Peptide FAQ
BPC-157 may accelerate recovery from musculoskeletal injury and illness as well as improve gut health, wound healing, and neurological function.
BPC-157 may accelerate recovery from injury and illness, improve gut health and improve neurological functioning.
Peptides are large proteins composed of amino acid chains and regulate a wide range of biological functions. Peptides signal and trigger the body’s molecules and cells to perform specific healing tasks vital to our health and well-being.
About 7,000 naturally occurring peptides have been identified, and medical treatment with natural or artificially created peptides is currently the focus of intense study.
The first therapeutic peptide synthesized and used for human treatment was insulin in 1921. Since then, remarkable achievements have been made resulting in the approval of more than 33 peptide drugs worldwide since 2000. Many more are under current investigation.
Advantages of large-molecule peptide therapy over other medication classes include very high specificity i.e., they typically do not bind to anything other than their intended receptor. This can result in significantly higher effectiveness and a generally lower side effect profile than other classes of medications.
The field of peptide therapy is expanding rapidly, and a wide variety of conditions can be treated with peptides.
Conditions treated include:
- Boosting hormone levels
- Improving sleep quality
- Stimulating hair growth
- Enhancing cognitive function
- Treating sexual dysfunction
- Decreasing joint and muscle pain
- Increasing muscle mass
- Increasing weight loss
- Promoting immune function
- Increasing energy
Schedule a free virtual consultation with Dr. Justl Ellis to discuss your medical needs and to see if peptide therapy might be right for you!
We offer a variety of individual peptide therapies, each with their own unique physiologic effects and mechanisms of action. Synergistic combinations of certain peptides are also available.
For a full description of each peptide, please review the “All Medications” section of the Recess Rx homepage.
ANTI-AGING
- FOXO4-DRI
- Humanin
- MOTS-C
- SS-31 (Elamipretide)
BRAIN HEALTH
- Dihexa
- Selank (TP-7)
- Semax
WEIGHT LOSS
- Semaglutide
- Tirzepatide
GUT HEALTH
- BPC-157
- BPC-157/Thymosin Beta 4
GROWTH HORMONE RELEASE
- CJC-1295
- CJC-1295/Ipamorelin
- Ibutamoren
- Ipamorelin
- Sermorelin
- Sermorelin/Ipamorelin
- Tesamorelin/Ipamorelin
SEXUAL FUNCTION
- PT-141 Bremelanotide
SKIN HEALTH
- GHK-Cu
- LL-37
SLEEP THERAPY
- DSIP (Delta Sleep Inducing Peptide)
TISSUE RECOVERY
- BPC-157
- BPC-157/Thymosin Beta 4
Peptide therapy is a rapidly evolving field with a wide variety of newly available treatments.
Certain peptides, such as the GLP-1 weight loss peptides, are FDA approved therapies have been studied extensively and have been conclusively shown to be tremendously effective in human treatment populations.
Many other peptides show significant promise in animal studies and theoretical models and are being demonstrated anecdotally and in small human studies as being safe and effective. Most peptide therapies are not yet FDA approved and treatment with them should be considered experimental.
Schedule a consultation with Dr. Justl Ellis to discuss the efficacy and safety of the individual peptide therapy you are interested in.
Side effects of peptide therapy are generally mild but are usually related to their target receptor.
For example, GLP-1 weight loss medications slow gastric emptying and as such may cause nausea and other gastrointestinal side effects.
As another example, DSIP (Delta Sleep Inducing Peptide) is taken to improve sleep duration and quality but in some cases may result in drowsiness.
A full discussion of the known side effect profiles of each peptide can be found by clicking on the individual peptide under the “All Medications” section of the Recess Rx homepage.
Most peptides are refrigerated, short-shelf-life medications administered by subcutaneous injection. Some peptides may be taken by mouth.
A comprehensive review article published in a peer reviewed journal discussing current applications and future directions for peptide therapies may be found here.
For more specific information, refer to the individual peptides listed in the “All Medications” section of the homepage.
male hrt FAQ
Testosterone levels fall ~2% per year after 40. 20% of 60+ men over 60 and 50% of 80+ men have low levels. Clin Interv Aging 2008
Testosterone levels fall ~2% per year after 40. 20% of 60+ men and 50% of 80+ men have levels below the normal range. Clin Interv Aging 2008
Testosterone is a critical hormone which plays multiple important roles in the body, such as the development of male secondary sexual characteristics during puberty, development and maintenance of muscle mass and strength, maintenance of bone strength, sex drive, and fertility and sperm production.
As men age, testosterone levels drop very gradually, about 1% to 2% each year. More than a third of men over age 45 may have reduced levels of testosterone than might be considered normal.
There are also a variety of conditions that may result in low testosterone other than normal aging, such as pituitary conditions, direct injury or damage to the testes, certain medications, and autoimmune conditions, among others.
Testosterone levels have also been declining in otherwise healthy younger men over the last decades. Reasons for this are multi-factorial.
Men who have low testosterone levels and are suffering from undesirable symptoms could benefit from hormone replacement therapy.
Men with laboratory confirmed testosterone levels below the 60th percentile for age AND symptoms of testosterone deficiency are eligible for testosterone replacement therapy.
An initial consultation with Dr. Justl Ellis as well as laboratory testing to confirm the diagnosis of low testosterone is required prior to starting treatment
Testosterone replacement therapy by Recess Rx is intended solely for treatment of the medical condition of low testosterone and will not be prescribed for recreational, performance enhancing, or other uses.
A reasonable goal for treatment is maintenance of testosterone levels at above the 75th percentile for age. Testosterone levels during treatment will be monitored and dosing will be decreased if serum testosterone levels increase above the 99th percentile for age.
Symptoms of testosterone deficiency in adult men include reduced body and facial hair, loss of muscle mass, low libido, impotence, small testicles, reduced sperm count and infertility, irritability, poor concentration and depression, and brittle bones.
Treatment with testosterone should improve the symptoms of low testosterone. Increasing muscle mass, higher libido, improved sexual function, and improved mood may occur during treatment.
Many symptoms that can be attributed to low testosterone could also be caused by other factors (such as clinical depression, other physiologic reasons for low libido, etc). Responses to testosterone replacement therapy are individual and results of treatment are not guaranteed.
Testosterone replacement therapy may cause higher than normal red blood cell counts (polycythemia), which may increase the risk of heart problems or blood clots. While rare, when these complications occur, they may be serious or even life-threatening.
Testosterone treatment may cause enlargement of the prostate, which may result in difficulty urinating or an increased risk of urinary tract infections. Testosterone supplementation may also decrease sperm production and decrease fertility.
Minor side effects of testosterone therapy include gynecomastia (development of increasing breast tissue in males), acne, and depression.
This list of side effects is not comprehensive. An FDA document fully describing the indications, risks, and benefits of testosterone replacement therapy with testosterone cypionate can be reviewed by clicking here.
Testosterone replacement is contraindicated (not allowed) in persons with a known allergy to testosterone cypionate or any of its components and in men with breast cancer or prostate cancer.
For direct hormone replacement, we most commonly prescribe injectable testosterone cypionate, which is a long-acting form of testosterone typically administered by intramuscular injection once a week. Customized and alternative regimens (i.e., combining testosterone with nandrolone to improve the side effect profile) are available.
Alternative regimens to increase natural production of testosterone are also available. Examples of medications used include enclomiphene, gonadorelin, and kisspeptin-10. The route and frequency of administration of these medications depends on the medication and individual patient factors.
For details about the medications we use, please refer to the individual medications listed under the “Men’s Hormone” section of the “All Medications” section of the homepage.
Schedule a consultation with Dr. Justl Ellis to determine which regimen might be right for you. Once ordered, medication will be delivered to your home along with instructions and supplies for self-administration.
female hrt FAQ
Hormonal imbalances due to menopause, PCOS, obesity, or other conditions can cause significant dysfunction. HRT can help!
Direct hormone replacement can improve symptoms related to PCOS, obesity, menopause, and many other hormonal conditions.
The hormonal system and monthly cycle in women is complex! Estrogen, progesterone, and other hormones all must be in balance to maintain female fertility and physiologic function.
Most women are aware that menopause can cause significant and dramatic hormonal changes. Fewer are aware that there are many issues that can affect younger women’s hormones as well, such as polycystic ovarian syndrome (PCOS) to being obese or underweight, among others.
If you are suffering from hot flashes, mood changes, poor sleep quality, low energy, or poor sexual function, abnormal hormone levels may be part of the cause. Hormone replacement therapy can be part of the solution!
Getting your hormones checked with Recess Rx is a low-cost and convenient way to put you on the path to treatment and wellness.
If your hormones are identified as being out of balance, many different types of medications can be used to improve your levels and also improve your level of function.
Most women with hormone levels outside of the normal range are potential candidates for hormone replacement or modulating therapy.
Depending on the hormones involved, some patients may have conditions that prevent them from being candidates for treatment.
HRT is an individual decision that each woman should make after a comprehensive discussion of risks and benefits with a qualified physician.
Treatment regimens are individualized and depend on your own lab results and symptoms.
Direct estrogen replacement with either estradiol or estriol (or a combination of both) is the most commonly used hormone replacement therapy.
Estrogen is usually taken transdermally via a topical cream or patch. Oral estrogens are available but carry significant risks.
Direct progesterone replacement can be accomplished via dissolving troches, topical creams, and vaginal suppositories.
Additional supporting medications such as DHEA, testosterone, and others may also be prescribed on an individual basis.
There are many benefits of bioidentical hormone replacement therapy, including:
- Reduction in direct hormonally related symptoms such as mood swings, low energy, hot flashes, and night sweats
- Lowering of risk of heart attack, stroke, and blood clots
- Reduced risk of breast cancer
- Reduced risk of osteopenia and osteoporosis
- Improved sleep quality
- Improved mood
- Improved cognition and brain health
- Reduced all-cause mortality for under-60 women in their first 10 years of menopause
- Decreased anxiety and depression in certain populations
Responses to hormone replacement therapy are individual and results are not guaranteed.
Schedule a consultation with Dr. Justl Ellis to get your labs checked and see if hormone replacement might be right for you!
Risks of HRT vary with the type, dose, route of administration, duration of use, and age of initiation.
Historically, treatment with oral estrogens had been shown to increase the risks of breast and uterine cancer, cardiovascular events, and blood clots.
Modern HRT regimens significantly reduce or even eliminate these risks by reducing the doses used and using different methods of application (such as topical creams, and vaginal suppositories).
We give the smallest doses needed of the safest possible preparations to achieve the patient’s desired treatment goals.
Hormone replacement therapy with estrogens is absolutely contraindicated in women with:
- Unexplained vaginal bleeding
- Estrogen-sensitive breast and endometrial cancers or a genetically elevated risk of breast cancer
- A history of blood clots or blood clotting disorders
- A history of coronary artery disease or stroke
- A history of elevated triglyceride levels or gallbladder disease
- A history of liver disease.
Discuss your individual medical history with Dr. Justl Ellis during your consultation.
Review the “Women’s Hormone” section under the “All Medications” section of the homepage for detailed information on the medications we prescribe.
An easy-to-understand PDF guide to HRT written by the Veteran’s Administration can be reviewed by clicking here.
A comprehensive, peer-reviewed journal review of the topic of HRT in menopause can be reviewed by clicking here.
GENERAL FAQ
Drug compounding is the process of combining, mixing, or altering ingredients to create a medication tailored to the needs of an individual patient.
Our compounded medications contain the same active pharmaceutical ingredients as “name brand” medications and are available at a significantly lower cost.
In some cases, medications are formulated with additional compounds to increase their effectiveness or help decrease side effects. For example, our tirzepatide is compounded with either pyridoxine (to decrease nausea) or levocarnitine (to help with lean mass maintenance during weight loss).
Third-party testing for purity, potency, and sterility is performed on all sourced medications to ensure the highest quality and effectiveness.
We obtain our medications from fully licensed and independently inspected compounding pharmacies within the state of Texas.
The two pharmacies we primarily use are Texas Star Pharmacy in Plano and Grand Avenue Pharmacy in Austin.
Medication orders will be submitted to our pharmacy partners the same day they are purchased. Medications are shipped directly to your home address and typically arrive within 1-5 business days depending on your address and whether your medications require refrigeration.
Most medications will ship the next business day after the order is placed and will be sent from either Plano or Austin.
Yes! Any patient who refers another patient to Recess Rx who purchases a medication or subscription will receive a $50 credit on their next order or subscription price. There is no limit to the number of patients you can refer!
Yes! You may use Health Savings Account (HSA) funds to cover your membership cost—and many people recoup the entire cost of their membership via lower food costs alone.
We do not accept commercial insurance. However, you may use Health Savings Account (HSA) funds to cover your membership cost.
Drug compounding is the process of combining, mixing, or altering ingredients to create a medication tailored to the needs of an individual patient.
Our compounded medications contain the same active pharmaceutical ingredients as “name brand” medications and are available at a significantly lower cost.
In some cases, medications are formulated with additional compounds to increase their effectiveness or help decrease side effects. For example, our tirzepatide is compounded with either pyridoxine (to decrease nausea) or levocarnitine (to help with lean mass maintenance during weight loss).
Third-party testing for purity, potency, and sterility is performed on all sourced medications to ensure the highest quality and effectiveness.
We obtain our medications from fully licensed and independently inspected compounding pharmacies within the state of Texas.
The two pharmacies we primarily use are Texas Star Pharmacy in Plano and Grand Avenue Pharmacy in Austin.
Medication orders will be submitted to our pharmacy partners the same day they are purchased. Medications are shipped directly to your home address and typically arrive within 1-5 business days depending on your address and whether your medications require refrigeration.
Most medications will ship the next business day after the order is placed and will be sent from either Plano or Austin.
Yes! Any patient who refers another patient to Recess Rx who purchases a medication or subscription will receive a $50 credit on their next order or subscription price. There is no limit to the number of patients you can refer!
Yes! You may use Health Savings Account (HSA) funds to cover your membership cost—and many people recoup the entire cost of their membership via lower food costs alone.
We do not accept commercial insurance. However, you may use Health Savings Account (HSA) funds to cover your membership cost.
FOXO4-DRI Peptide
INDICATIONS AND USAGE:
- FOXO4-DRI is an experimental peptide therapy used for anti-aging purposes, aiming to reduce cellular senescence and promote healthy aging.
- It is primarily researched for its potential to rejuvenate tissues and improve longevity by targeting age-related cellular damage.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis to sign up.
AMOUNT | COST |
---|---|
50mg vial (10mg/mL x 5mL) | $620 |
SUGGESTED PROTOCOLS:
- 0.3mg-0.5mg daily for 7 days, every other week
- 2mg-10mg bi-weekly for four weeks
MECHANISM OF ACTION:
- FOXO4-DRI interferes with the interaction between the FOXO4 protein and p53, a key regulator of cellular senescence.
- By disrupting this interaction, FOXO4-DRI promotes the selective elimination of senescent cells, which are cells that have stopped dividing and contribute to age-related tissue dysfunction. Removing these cells helps restore tissue function and enhances regenerative capacity.
COMMON SIDE EFFECTS:
- As an experimental therapy, there is limited data on side effects. Potential risks may include immune reactions, fatigue, or localized inflammation at the injection site. Long-term effects are not well established.
CONTRAINDICATIONS:
- There are no established contraindications due to the experimental nature of the therapy, but it should be avoided in individuals with active infections, autoimmune conditions, or hypersensitivity to peptide therapies.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (experimental therapy)
- Huang Y et al (2021) Senolytic Peptide FOXO4-DRI Selectively Removes Senescent Cells From in vitro Expanded Human Chondrocytes. 2021 Front. Bioeng. Biotechnol. 9:677576.
- Serrano, M. Tools to eliminate senescent cells. Nature 545, 294–295 (2017).
- Baar MP et al. Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging. Cell. 2017 Mar 23;169(1):132-147.e16.
- Xiang-qiang et al. Expression and clinical significance of FOX04 in colorectal cancer. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2011 Sep;27(9):969-71.
- Le, Hillary H. et al. Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells. eBioMedicine, Vol. 73, 103646
MOTS-C Peptide
INDICATIONS AND USAGE:
- MOTS-C is a mitochondrial-derived peptide that supports metabolic health and cellular energy, often used for anti-aging purposes and metabolic disorders like obesity or type 2 diabetes.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
50mg vial (10mg/mL x 5mL) | $620 |
SUGGESTED PROTOCOL:
- 5mg every 5 days for 20 days, repeated once every 6 months
MECHANISM OF ACTION:
- MOTS-C improves metabolic function by regulating glucose metabolism and enhancing mitochondrial energy production. It activates pathways that improve insulin sensitivity and promote cellular adaptation to stress, supporting overall metabolic health.
COMMON SIDE EFFECTS:
- Potential side effects are not well-documented, but may include fatigue, dizziness, or mild gastrointestinal symptoms. Long-term safety data is limited due to the peptide’s experimental status.
CONTRAINDICATIONS:
- MOTS-C should be avoided in individuals with known allergies to peptides or active autoimmune conditions. It is not recommended for use in pregnant or breastfeeding individuals.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (experimental therapy)
- Lee C, et al. MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism. Free Radic Biol Med. 2016 Nov;100:182-187.
- Lu H et al. MOTS-c peptide regulates adipose homeostasis to prevent ovariectomy-induced metabolic dysfunction. J Mol Med (Berl). 2019 Apr;97(4):473-485.
- Che N et al. MOTS-c improves osteoporosis by promoting the synthesis of type I collagen in osteoblasts via TGF-β/SMAD signaling pathway. Eur Rev Med Pharmacol Sci. 2019 Apr;23(8):3183-3189.
- Yang Y et al. The role of mitochondria-derived peptides in cardiovascular disease: Recent updates. Biomed Pharmacother. 2019 Sep;117:109075.
SS-31 (Elamipretide) Peptide
INDICATIONS AND USAGE:
- SS-31, also known as Elamipretide, is a peptide therapy used to improve mitochondrial function and reduce oxidative stress, potentially benefiting conditions related to aging, such as muscle weakness and heart failure.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
200mg vial (40mg/mL x 5mL) | $510 |
SUGGESTED PROTOCOLS:
- 10mg injected subcutaneously daily for 30 days
MECHANISM OF ACTION:
- SS-31 targets the inner mitochondrial membrane, binding to cardiolipin, a phospholipid critical for mitochondrial function. This stabilizes the mitochondrial structure, reduces reactive oxygen species (ROS) production, and improves cellular energy production.
COMMON SIDE EFFECTS:
- Reported side effects include injection site reactions, fatigue, headaches, and transient muscle soreness. It may cause mild gastrointestinal symptoms in some individuals.
CONTRAINDICATIONS:
- SS-31 should not be used in individuals with known hypersensitivity to the peptide. Caution is advised in those with active autoimmune diseases or mitochondrial disorders.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (experimental therapy)
- Chatfield et al. Elamipretide Improves Mitochondrial Function in the Failing Human Heart. JACC Basic Transl Sci. 2019 Apr 29;4(2):147–157.
- Karaa et al. Efficacy and Safety of Elamipretide in Individuals With Primary Mitochondrial Myopathy: The MMPOWER-3 Randomized Controlled Trial. Neurology. 2023 Jul 18;101(3):e238–e252.
- Karaa A, Haas R, Goldstein A, Vockley J, Cohen BH. A randomized crossover trial of elamipretide in adults with primary mitochondrial myopathy. J Cachexia Sarcopenia Muscle. 2020 Aug;11(4):909-918.
Dihexa (PNB-0408) Peptide
INDICATIONS AND USAGE:
- Dihexa is a nootropic peptide used for cognitive enhancement and potential treatment of neurodegenerative conditions such as Alzheimer’s disease. It is known to promote synaptogenesis and neuronal growth.
ADMINISTRATION ROUTE:
- Oral Capsules
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
5mg capsule (#30) | $310 |
10mg capsule (#30) | $380 |
20mg capsule (#30) | $430 |
SUGGESTED PROTOCOL:
- One capsule daily for 30 days
MECHANISM OF ACTION:
- Dihexa is thought to function by binding to hepatocyte growth factor (HGF) and its receptor, c-Met, which plays a crucial role in neuronal growth and synaptic plasticity. This interaction enhances neurogenesis and supports the repair and regeneration of damaged neurons, potentially improving cognitive function.
COMMON SIDE EFFECTS:
- Limited data is available, but potential side effects may include headaches, fatigue, or dizziness. Long-term safety and efficacy have not been well established due to its experimental status.
CONTRAINDICATIONS:
- Dihexa should be avoided in individuals with a history of peptide allergies or active central nervous system infections. It is not recommended for use during pregnancy or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (experimental therapy)
- Sun X et al. Angiotensin IV-Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP/PS1 Mouse via the PI3K/AKT Signaling Pathway. Brain Sci. 2021 Nov 11;11(11):1487.
- Wright JW et al. The Brain Hepatocyte Growth Factor/c-Met Receptor System: A New Target for the Treatment of Alzheimer’s Disease. J Alzheimers Dis. 2015;45(4):985-1000.
- Wright JW et al. The development of small molecule angiotensin IV analogs to treat Alzheimer’s and Parkinson’s diseases. Prog Neurobiol. 2015 Feb;125:26-46.
- Ho JK et al. Cognitive benefits of angiotensin IV and angiotensin-(1-7): A systematic review of experimental studies. Neurosci Biobehav Rev. 2018 Sep;92:209-225.
- McCoy AT et al. Evaluation of metabolically stabilized angiotensin IV analogs as procognitive/antidementia agents. J Pharmacol Exp Ther. 2013 Jan;344(1):141-54.
Selank (TP-7) Peptide
INDICATIONS AND USAGE:
- Selank, also known as TP-7, is a peptide used for its nootropic and anxiolytic effects. It is primarily used to alleviate anxiety, improve cognitive function, and enhance mood.
ADMINISTRATION ROUTE:
- Nasal Spray
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
40mg nasal spray (7.5mg/mL x 5mL) | $260 |
50mg nasal spray (10mg/mL x 5mL) | $260 |
SUGGESTED PROTOCOL:
- 1-2 sprays intranasally (150-300mcg) per day for 14 days, with 7 days in between cycles
MECHANISM OF ACTION:
- Selank modulates the activity of neurotransmitters, including serotonin and dopamine, which are involved in mood regulation and stress response. It also exhibits anti-inflammatory properties by influencing the expression of cytokines and supports brain-derived neurotrophic factor (BDNF) levels, enhancing neuroplasticity and cognitive performance.
COMMON SIDE EFFECTS:
- Common side effects may include mild headaches, fatigue, or nasal irritation (if administered intranasally). It is generally well tolerated, with few adverse effects reported.
CONTRAINDICATIONS:
- Selank is contraindicated in individuals with known hypersensitivity to peptides. It is not recommended for use during pregnancy or breastfeeding due to limited safety data.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (experimental peptide therapy)
- Volkova et al. Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission. Front Pharmacol. 2016 Feb 18;7:31.
- Uchakina et al. Immunomodulatory effects of selank in patients with anxiety-asthenic disorders. Zh Nevrol Psikhiatr Im S S Korsakova. 2008;108(5):71-5.
- Zozulia et al. Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia. Zh Nevrol Psikhiatr Im S S Korsakova. 2008;108(4):38-48.
- Sokolov et al. Effects of Selank on behavioral reactions and activities of plasma enkephalin-degrading enzymes in mice with different phenotypes of emotional and stress reactions. Bull Exp Biol Med. 2002 Feb;133(2):133-5.
Semax Peptide
INDICATIONS AND USAGE:
- Semax is a nootropic peptide used for cognitive enhancement, neuroprotection, and the treatment of conditions such as stroke recovery and optic nerve damage.
ADMINISTRATION ROUTE:
- Nasal Spray
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
40mg nasal spray (7.5mg/mL x 5mL) | $260 |
50mg nasal spray (10mg/mL x 5mL) | $260 |
SUGGESTED PROTOCOL:
- 1-2 sprays (600-1000mcg) intranasally daily for four weeks
MECHANISM OF ACTION:
- Semax is believed to enhance levels of brain-derived neurotrophic factor (BDNF), which supports neuroplasticity and the repair of neurons. It also modulates neurotransmitter levels, such as dopamine and serotonin, potentially improving mood, cognition, and mental clarity.
COMMON SIDE EFFECTS:
- Reported side effects are typically mild and may include nasal irritation (when used as a nasal spray), headaches, or temporary mood changes.
CONTRAINDICATIONS:
- Semax should not be used by individuals with known hypersensitivity to the peptide or in those with active neurological infections. It is not recommended for use during pregnancy or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (experimental therapy)
- Lebedeva et al. Effects of Semax on the Default Mode Network of the Brain. Bull Exp Biol Med. 2018 Sep;165(5):653-656
- Gusev EI et al. The efficacy of semax in the treatment of patients at different stages of ischemic stroke. Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(3. Vyp. 2):61-68.
- Sciacca et al. Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models. ACS Chem Neurosci. 2022 Feb 16;13(4):486-496.
GHK-Cu (Copper Peptide)
INDICATIONS AND USAGE:
- GHK-Cu is a copper peptide used in hair restoration and skin care to promote hair growth, improve scalp health, and enhance skin regeneration.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
- Topical Cream
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
50mg vial (10mg/mL x 5mL) | $280 |
0.5% topical cream (30mL) | $300 |
SUGGESTED PROTOCOLS:
- Subcutaneous injection: 1mg daily
- Topical Cream: Apply one pump of medication to affected area two times per day
MECHANISM OF ACTION:
- GHK-Cu promotes tissue regeneration and healing by increasing the production of collagen and other extracellular matrix components. In hair restoration, it stimulates hair follicle activity and supports the health of the scalp by promoting blood vessel growth and reducing inflammation.
COMMON SIDE EFFECTS:
- Side effects are generally minimal but may include temporary scalp irritation, redness, or itching.
CONTRAINDICATIONS:
- GHK-Cu should not be used by individuals with known allergies to copper or peptide-based products. It is also not recommended for use during pregnancy or breastfeeding without medical consultation.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available
- Pickart L et al. The human tri-peptide GHK and tissue remodeling. J Biomater Sci Polym Ed. 2008;19(8):969-988.
- Maquart FX et al. Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex GHK-Cu. FEBS Lett. 1988 Nov;238(2):343-346.
- Pickart L et al. GHK-Cu may prevent oxidative stress in skin by regulating copper and modifying expression of numerous antioxidant genes. Cosmetics. 2015 Jun;2(3):236-247.
- Pickart L et al. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018 Jul 7;19(7):1987.
GHK-Cu + Biotin Topical Scalp Foam
INDICATIONS AND USAGE:
- This combination is used for hair restoration to promote hair growth and scalp health. It is formulated with GHK-Cu to stimulate hair follicles and Biotin to strengthen hair strands.
ADMINISTRATION ROUTE:
- Topical Foam
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
0.5%-0.5% topical foam (30mL) | $280 |
SUGGESTED PROTOCOL:
- Apply one pump of foam to head and massage into scalp up to two times daily
MECHANISM OF ACTION:
- GHK-Cu enhances tissue regeneration and hair follicle activity, while Biotin, a B-vitamin, supports keratin production to strengthen hair. Together, they work synergistically to improve hair density and reduce shedding.
COMMON SIDE EFFECTS:
- Possible side effects include scalp irritation, itching, or redness, especially if the product is used on broken or sensitive skin.
CONTRAINDICATIONS:
- Individuals with a history of allergies to copper peptides, biotin, or other ingredients in the foam should avoid using this product. Use during pregnancy or breastfeeding should be discussed with a healthcare professional.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available
- Pickart L et al. The human tri-peptide GHK and tissue remodeling. J Biomater Sci Polym Ed. 2008;19(8):969-988.
- Maquart FX et al. Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex GHK-Cu. FEBS Lett. 1988 Nov;238(2):343-346.
- Pickart L et al. GHK-Cu may prevent oxidative stress in skin by regulating copper and modifying expression of numerous antioxidant genes. Cosmetics. 2015 Jun;2(3):236-247.
- Pickart L et al. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018 Jul 7;19(7):1987.
Bimatoprost Solution
INDICATIONS AND USAGE:
- Bimatoprost is used to enhance eyelash growth and may also be used off-label for promoting hair growth on the scalp.
ADMINISTRATION ROUTE:
- Topical Solution
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
0.03% topical solution (5mL) | $130 |
SUGGESTED PROTOCOL:
- Apply one drop of medication nightly along the skin of the upper eyelid at base of lashes.
MECHANISM OF ACTION:
- Bimatoprost is a prostaglandin analog that prolongs the growth phase (anagen phase) of hair follicles, resulting in longer, thicker, and darker eyelashes. Its effect on hair follicles on the scalp is thought to be similar, though less well-studied.
COMMON SIDE EFFECTS:
- Common side effects include eye irritation (when used near the eyes), darkening of the skin around the treated area, or hair growth in unintended areas if the medication spreads beyond the application site.
CONTRAINDICATIONS:
- Bimatoprost is contraindicated in individuals with a history of eye conditions such as uveitis or those at risk for macular edema. It should not be used during pregnancy or breastfeeding without consulting a healthcare professional.
MORE INFORMATION:
- FDA Data Safety Sheet for Bimatoprost: Not Available
- Wirta D et al. Bimatoprost 0.03% for the Treatment of Eyelash Hypotrichosis: A Pooled Safety Analysis of Six Randomized, Double-masked Clinical Trials. J Clin Aesthet Dermatol. 2015 Jul;8(7):17-29.
- Cohen JL. Enhancing the growth of natural eyelashes: the mechanism of bimatoprost-induced eyelash growth. Dermatol Surg. 2010 Sep;36(9):1361-71.
- Johnstone MA et al. Prostaglandin-induced hair growth. Surv Ophthalmol. 2010 Nov;55(5):424-431.
- Glaser DA et al. Long-term safety and efficacy of bimatoprost solution 0·03% application to the eyelid margin for the treatment of idiopathic and chemotherapy-induced eyelash hypotrichosis: a randomized controlled trial. Br J Dermatol. 2015;172(5):1384-94.
Finasteride + Biotin + Vitamin C
INDICATIONS AND USAGE:
- This oral combination is used to treat hair loss by reducing hair follicle miniaturization and providing essential nutrients for hair growth.
ADMINISTRATION ROUTE:
- Oral Capsule
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
1mg-2.5mg-100mg capsule (#60) | $130 |
1mg-2.5mg-100mg capsule (#90) | $160 |
SUGGESTED PROTOCOL:
- Take one capsule by mouth daily.
MECHANISM OF ACTION:
- Finasteride inhibits the conversion of testosterone to dihydrotestosterone (DHT), a hormone that contributes to hair loss. Biotin supports keratin production, while Vitamin C serves as an antioxidant, promoting healthy scalp conditions.
COMMON SIDE EFFECTS:
- Common side effects may include decreased libido, erectile dysfunction, or breast tenderness (due to Finasteride). Biotin and Vitamin C are generally well-tolerated but can occasionally cause digestive discomfort.
CONTRAINDICATIONS:
- Finasteride is contraindicated in women who are pregnant or may become pregnant, as it can cause birth defects. Caution is advised in individuals with known allergies to any of the components.
MORE INFORMATION:
- FDA Data Safety Sheet for Finasteride
- Kaufman KD et al. Finasteride in the treatment of men with androgenetic alopecia. J Am Acad Dermatol. 1998 Oct;39(4 Pt 1):578-589.
- Arca E et al. An open, randomized, comparative study of oral finasteride and 5% topical minoxidil in male androgenetic alopecia. Dermatology. 2004;209(2):117-25.
- Rossi A et al. Finasteride, 1 mg daily administration on male androgenetic alopecia in different age groups: 10-year follow-up. Dermatol Ther. 2011 Jul-Aug;24(4):455-61.
- Leyden J et al. Finasteride in the treatment of men with frontal male pattern hair loss. J Am Acad Dermatol. 1999 Sep;40(6 Pt 1):930-937.
Minoxidil + Finasteride + Retinoic Acid + Fluocinolone Topical Scalp Solution
INDICATIONS AND USAGE:
- This topical combination is used to treat hair loss by stimulating hair growth and addressing scalp conditions that may hinder hair regrowth.
ADMINISTRATION ROUTE:
- Topical Scalp Solution
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
5%-0.1%-.01%-.01% topical solution (30mL) | $130 |
5%-0.1%-.01%-.01% topical solution (90mL) | $190 |
5%-0.1%-.025%-.025% topical solution (30mL) | $170 |
5%-0.1%-.025%-.025% topical solution (90mL) | $190 |
SUGGESTED PROTOCOL:
- Apply enough solution to moisten scalp and massage in with fingertips daily. Wash hands after application.
MECHANISM OF ACTION:
- Minoxidil is a vasodilator that increases blood flow to hair follicles, promoting growth. Finasteride reduces DHT levels in the scalp. Retinoic Acid enhances absorption of the active ingredients, while Fluocinolone, a corticosteroid, reduces inflammation.
COMMON SIDE EFFECTS:
- Side effects may include scalp irritation, itching, or redness. There is also a risk of systemic absorption of Finasteride, potentially leading to sexual side effects.
CONTRAINDICATIONS:
- This combination should not be used by individuals with scalp infections, open wounds, or known allergies to any components. It is contraindicated during pregnancy due to the presence of Finasteride.
MORE INFORMATION:
- FDA Data Safety Sheet for Minoxidil
- FDA Data Safety Sheet for Finasteride
- Lee SW et al. A Systematic Review of Topical Finasteride in the Treatment of Androgenetic Alopecia in Men and Women. J Drugs Dermatol. 2018 Apr 1;17(4):457-463.
- Devjani S et al. Androgenetic Alopecia: Therapy Update. Drugs. 2023 Jun;83(8):701-715.
- Suchonwanit P et al. A randomized, double-blind controlled study of the efficacy and safety of topical solution of 0.25% finasteride admixed with 3% minoxidil vs. 3% minoxidil solution in the treatment of male androgenetic alopecia. J Eur Acad Dermatol Venereol. 2018 Dec;32(12):2257-2263.
- Sung CT et al. The Efficacy of Topical Minoxidil for Non-Scarring Alopecia: A Systematic Review. J Drugs Dermatol. 2019 Feb 1;18(2):155-160.
Minoxidil + Finasteride Topical Scalp Solution
INDICATIONS AND USAGE:
- This topical combination is used to treat hair loss by stimulating hair growth and addressing scalp conditions that may hinder hair regrowth.
ADMINISTRATION ROUTE:
- Topical Scalp Solution
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
5%-0.1% topical solution (30 Day Supply) | $140 |
5%-0.1% topical solution (90 Day Supply) | $300 |
SUGGESTED PROTOCOL:
- Apply enough solution to moisten scalp and massage in with fingertips daily. Wash hands after application.
MECHANISM OF ACTION:
- Minoxidil is a vasodilator that increases blood flow to hair follicles, promoting growth. Finasteride reduces DHT levels in the scalp.
COMMON SIDE EFFECTS:
- Side effects may include scalp irritation, itching, or redness. There is also a risk of systemic absorption of Finasteride, potentially leading to sexual side effects.
CONTRAINDICATIONS:
- This combination should not be used by individuals with scalp infections, open wounds, or known allergies to any components. It is contraindicated during pregnancy due to the presence of Finasteride.
MORE INFORMATION:
- FDA Data Safety Sheet for Minoxidil
- FDA Data Safety Sheet for Finasteride
- Lee SW et al. A Systematic Review of Topical Finasteride in the Treatment of Androgenetic Alopecia in Men and Women. J Drugs Dermatol. 2018 Apr 1;17(4):457-463.
- Devjani S et al. Androgenetic Alopecia: Therapy Update. Drugs. 2023 Jun;83(8):701-715.
- Suchonwanit P et al. A randomized, double-blind controlled study of the efficacy and safety of topical solution of 0.25% finasteride admixed with 3% minoxidil vs. 3% minoxidil solution in the treatment of male androgenetic alopecia. J Eur Acad Dermatol Venereol. 2018 Dec;32(12):2257-2263.
- Sung CT et al. The Efficacy of Topical Minoxidil for Non-Scarring Alopecia: A Systematic Review. J Drugs Dermatol. 2019 Feb 1;18(2):155-160.
CJC-1295 Peptide
INDICATIONS AND USAGE:
- CJC-1295 is a growth hormone-releasing hormone (GHRH) analog used to increase growth hormone levels in the body, promoting muscle growth, fat loss, and anti-aging effects.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
10mg vial (2mg/mL x 5mL) | $340 |
SUGGESTED PROTOCOL:
- 30-60mcg/kg once a week for 12 weeks, followed by 4 weeks off
MECHANISM OF ACTION:
- CJC-1295 binds to GHRH receptors in the pituitary gland, stimulating the release of growth hormone. Its long-acting nature increases the half-life of endogenous GHRH, allowing for more stable and prolonged growth hormone release.
COMMON SIDE EFFECTS:
- Potential side effects include injection site reactions, water retention, flushing, or dizziness. Some users may experience an increase in appetite or mild numbness.
CONTRAINDICATIONS:
- CJC-1295 should be avoided in individuals with a history of cancer or growth-related disorders. It is not recommended for use during pregnancy or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (research peptide therapy)
- Teichman SL et al. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. 2006 Mar;91(3):799-805.
- Ionescu M et al. Pulsatile Secretion of Growth Hormone in Response to Continuous Infusion of CJC-1295 in Healthy Men. J Clin Endocrinol Metab 2006;91:4792-4797.
- Alba M et al. Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse. Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1290-4.
Ibutamoren (MK-677)
INDICATIONS AND USAGE:
- Ibutamoren is used to increase growth hormone levels and insulin-like growth factor 1 (IGF-1) to promote muscle growth, fat loss, and improve sleep quality. It is often used for anti-aging, bodybuilding, or in individuals with growth hormone deficiencies.
ADMINISTRATION ROUTE:
- Oral Capsule
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
25mg capsule (#30) | $250 |
25mg capsule (#60) | $470 |
25mg capsule (#90) | $540 |
50mg capsule (#30) | $310 |
50mg capsule (#60) | $590 |
50mg capsule (#90) | $710 |
SUGGESTED PROTOCOL:
- Take one capsule daily before bed
MECHANISM OF ACTION:
- Ibutamoren is a growth hormone secretagogue that mimics ghrelin, a hormone that stimulates growth hormone secretion. It activates the ghrelin receptor, leading to increased endogenous growth hormone and IGF-1 levels.
COMMON SIDE EFFECTS:
- Side effects may include increased appetite, water retention, fatigue, and mild joint pain. There is also a risk of insulin resistance with prolonged use.
CONTRAINDICATIONS:
- Ibutamoren should not be used by individuals with active cancer or those at risk of developing diabetes due to its effects on insulin sensitivity. It is not recommended for use during pregnancy or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (research compound)
- Nass, et al. Effects of an Oral Ghrelin Mimetic on Body Composition and Clinical Outcomes in Healthy Older Adults: A Randomized, Controlled Trial. Ann Intern Med. 2008 Nov 4;149(9):601–611..
- Smith RG, et al. Growth Hormone Secretagogues as Potential Therapeutic Agents to Restore Growth Hormone Secretion in Older Subjects to Those Observed in Young Adults. J Gerontol A Biol Sci Med Sci. 2023 Jun 16;78(Suppl 1):38–43.
- Patchett et al. Design and biological activities of L-163,191 (MK-0677): a potent, orally active growth hormone secretagogue. Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):7001-5.
- Sigalos JT et al. The Safety and Efficacy of Growth Hormone Secretagogues. Sex Med Rev. 2018 Jan;6(1):45-53.
- Murphy et al. MK-677, an orally active growth hormone secretagogue, reverses diet-induced catabolism. J Clin Endocrinol Metab. 1998 Feb;83(2):320-5.
Ipamorelin Peptide
INDICATIONS AND USAGE:
- Ipamorelin is a growth hormone-releasing peptide used to stimulate the natural production of growth hormone, often for anti-aging, fat loss, and muscle growth purposes.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
2mg/mL (5mL vial) | $280 |
SUGGESTED PROTOCOL:
- 100mcg-300mcg injected subcutaneously daily for 8-12 weeks, with a 4-week break between cycles
MECHANISM OF ACTION:
- Ipamorelin binds to growth hormone secretagogue receptors, promoting the release of growth hormone from the pituitary gland. It is selective and does not significantly affect cortisol or prolactin levels, making it a safer option for growth hormone stimulation.
COMMON SIDE EFFECTS:
- Common side effects include mild injection site reactions, water retention, or headaches. Some users may experience dizziness or flushing.
CONTRAINDICATIONS:
- Ipamorelin should be avoided in individuals with a history of cancer or growth disorders. It is not recommended for use during pregnancy or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (research peptide therapy)
- Raun K et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998 Nov;139(5):552-61.
- Salomon F, Cuneo RC, Hesp R, Sönksen PH. The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. N Engl J Med. 1989 Dec 28;321(26):1797-803.
- Chapman et al. Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of GH secretagogue in healthy elderly subjects. J Clin Endocrinol Metab 1996;81:745-752.
- Chapman et al. Oral administration of growth hormone (GH) releasing peptide-mimetic MK-677 stimulates the GH/insulin-like growth factor-I axis in selected GH-deficient adults. J Clin Endocrinol Metab. 1997 Oct;82(10):3455-63.
- Camanni F et al. Growth hormone-releasing peptides and their analogs. Front Neuroendocrinol. 1998 Jan;19(1):47-72.
Sermorelin Peptide
INDICATIONS AND USAGE:
- Sermorelin is a GHRH analog used to stimulate the production of growth hormone, primarily for anti-aging, muscle growth, and fat loss.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
9mg vial (1mg/mL x 9mL) | $220 |
15mg vial (3mg/mL x 5mL) | $280 |
SUGGESTED PROTOCOL:
- 0.2mg-0.3mg injected once daily at bedtime
MECHANISM OF ACTION:
- Sermorelin binds to GHRH receptors in the pituitary gland, promoting the release of endogenous growth hormone. It stimulates the natural pulsatile release of growth hormone, mimicking the body’s own growth hormone production process.
COMMON SIDE EFFECTS:
- Common side effects may include injection site irritation, flushing, dizziness, or headaches. It may also cause temporary numbness or tingling.
CONTRAINDICATIONS:
- Sermorelin is contraindicated in individuals with known hypersensitivity to the peptide or in those with active malignancies. It is not recommended during pregnancy or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (peptide therapy for research purposes)
- Salomon F, Cuneo RC, Hesp R, Sönksen PH. The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. N Engl J Med. 1989 Dec 28;321(26):1797-803.
- Chapman et al. Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of GH secretagogue in healthy elderly subjects. J Clin Endocrinol Metab 1996;81:745-752.
- Chapman et al. Oral administration of growth hormone (GH) releasing peptide-mimetic MK-677 stimulates the GH/insulin-like growth factor-I axis in selected GH-deficient adults. J Clin Endocrinol Metab. 1997 Oct;82(10):3455-63.
- Camanni F et al. Growth hormone-releasing peptides and their analogs. Front Neuroendocrinol. 1998 Jan;19(1):47-72.
Ipamorelin + CJC-1295 Combination
INDICATIONS AND USAGE:
- This combination is used to maximize growth hormone release, providing benefits such as increased muscle growth, fat loss, and anti-aging effects.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
10mg-10mg vial (2mg-2mg/mL x 5mL) | $390 |
SUGGESTED PROTOCOL:
- Inject 0.2mg-0.2mg (10 units) units subcutaneously morning and evening.
MECHANISM OF ACTION:
- The combination of Ipamorelin and CJC-1295 works synergistically to stimulate growth hormone production. CJC-1295 increases GHRH activity, while Ipamorelin stimulates the release of growth hormone from the pituitary, resulting in a more significant and sustained elevation in growth hormone levels.
COMMON SIDE EFFECTS:
- Possible side effects include injection site reactions, water retention, dizziness, or mild headaches. Users may also experience increased appetite or slight numbness.
CONTRAINDICATIONS:
- This combination should not be used by individuals with active cancer or those with growth-related conditions. It is also contraindicated during pregnancy or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (research peptide combination)
- See individual component pages on this website for research related to each medication
Ipamorelin + Sermorelin Combination
INDICATIONS AND USAGE:
- This combination is used to stimulate growth hormone production for anti-aging, muscle growth, and weight management.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
10mg-10mg vial (2mg-2mg/mL x 5mL) | $280 |
10mg-15mg vial (2mg-3mg/mL x 5mL) | $280 |
SUGGESTED PROTOCOL:
- Inject 10 units subcutaneously morning and evening.
MECHANISM OF ACTION:
- Sermorelin acts as a GHRH analog, while Ipamorelin works as a growth hormone secretagogue, both promoting natural growth hormone release. This dual action provides a more robust growth hormone stimulation than using either peptide alone.
COMMON SIDE EFFECTS:
- Side effects may include mild injection site irritation, dizziness, or headaches. There is also a potential for water retention or increased appetite.
CONTRAINDICATIONS:
- This combination is contraindicated in individuals with cancer, growth-related disorders, or hypersensitivity to peptide components. It should not be used during pregnancy or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (experimental therapy)
- See individual component pages on this website for research related to each medication
Ipamorelin + Tesamorelin Combination
INDICATIONS AND USAGE:
- This combination is used to enhance growth hormone secretion for muscle growth, fat loss, and metabolic health improvement.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
3mg-30mg vial (0.3mg-3mg/mL x 10mL) | $510 |
SUGGESTED PROTOCOL:
- Inject 10 units subcutaneously morning and evening.
MECHANISM OF ACTION:
- Tesamorelin stimulates GHRH receptors, promoting the release of growth hormone, while Ipamorelin directly stimulates the pituitary to release growth hormone. Together, they provide a powerful approach to increasing growth hormone levels and enhancing body composition.
COMMON SIDE EFFECTS:
- Potential side effects include injection site reactions, water retention, dizziness, or headaches. Some individuals may experience joint pain or increased appetite.
CONTRAINDICATIONS:
- The combination is contraindicated in individuals with active cancer, uncontrolled diabetes, or those with hypersensitivity to the components. It is not recommended for use during pregnancy or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (experimental therapy)
- See individual component pages on this website for research related to each medication
Melanotan II Peptide (Immune Support)
INDICATIONS AND USAGE:
- Melanotan II is a synthetic peptide used primarily for tanning by increasing skin pigmentation. It also has potential immune-modulating effects and may enhance sexual arousal.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
10mg vial (2mg/mL x 5mL) | $300 |
SUGGESTED PROTOCOL:
- 10 units (0.2mg) subcutaneously daily for 6-8 weeks
MECHANISM OF ACTION:
- Melanotan II mimics the action of alpha-melanocyte-stimulating hormone (α-MSH), which binds to melanocortin receptors in the skin, stimulating melanin production. This increased pigmentation protects the skin against UV radiation. It also binds to other melanocortin receptors involved in immune regulation and sexual function.
COMMON SIDE EFFECTS:
- Common side effects include nausea, flushing, headaches, and increased skin pigmentation in moles or freckles. There may also be temporary darkening of existing skin lesions.
CONTRAINDICATIONS:
- Melanotan II should not be used by individuals with a history of melanoma or skin cancer, as it may darken existing lesions. It is also contraindicated in those with known hypersensitivity to the peptide.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (research peptide)
- Ericson MD et al. Bench-top to clinical therapies: A review of melanocortin ligands from 1954 to 2016. Biochim Biophys Acta Mol Basis Dis. 2017 Oct;1863(10 Pt A):2414-2435.
LL-37 Peptide
INDICATIONS AND USAGE:
- LL-37 is an antimicrobial peptide used to support immune function and enhance the body’s defense against infections, including bacterial and viral infections.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
5mg vial (1mg/mL x 5mL) | $280 |
SUGGESTED PROTOCOL:
- 125mcg daily for four weeks, then four week break, then 125mcg daily for four weeks.
MECHANISM OF ACTION:
- LL-37 exhibits broad-spectrum antimicrobial activity by disrupting the cell membranes of bacteria, viruses, and fungi. It also modulates the immune response by promoting the recruitment of immune cells and reducing inflammation.
COMMON SIDE EFFECTS:
- Possible side effects may include localized irritation at the injection site, mild fatigue, or headache. Long-term safety is not well-established.
CONTRAINDICATIONS:
- LL-37 should be used cautiously in individuals with autoimmune conditions or hypersensitivity to peptides. It is not recommended for use during pregnancy or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (experimental therapy)
- Heilborn JD et al. The cathelicidin anti-microbial peptide LL-37 is involved in re-epithelialization of human skin wounds and is lacking in chronic ulcer epithelium. J Invest Dermatol. 2003 Mar;120(3):379-89.
- Nijnik A, et al. Human Cathelicidin Peptide LL-37 Modulates the Effects of IFN-γ on APCs. J Immunol 2009;183:5788-5798.
- Doss et al. Human defensins and LL-37 in mucosal immunity. J Leukoc Biol. 2010 Jan;87(1):79-92.
- Kahlenberg JM et al. Little peptide, big effects: the role of LL-37 in inflammation and autoimmune disease. J Immunol (2013) 191 (10): 4895–4901.
Thymosin Alpha-1 Peptide
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
15mg vial (3mg/mL x 5mL) | $270 |
SUGGESTED PROTOCOL:
- 1.6mg injected twice weekly
INDICATIONS AND USAGE:
- Thymosin Alpha-1 is used as an immune-modulating peptide to enhance the immune response, particularly in conditions such as chronic infections, cancer, or autoimmune diseases.
MECHANISM OF ACTION:
- Thymosin Alpha-1 stimulates the production and activity of T-cells, which are crucial for adaptive immune responses. It also reduces inflammation and improves the body’s ability to fight infections and cancer by modulating the activity of various immune cells.
COMMON SIDE EFFECTS:
- Common side effects may include mild injection site reactions, fatigue, or flu-like symptoms. It is generally well-tolerated with few adverse effects.
CONTRAINDICATIONS:
- Thymosin Alpha-1 is contraindicated in individuals with hypersensitivity to the peptide. Caution is advised in those with autoimmune disorders, as it may exacerbate symptoms.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (research peptide)
- Ancell CD et al. Thymosin alpha-1. Am J Health Syst Pharm. 2001 May 15;58(10):879-85.
- Matteucci C et al. Thymosin alpha 1 and HIV-1: recent advances and future perspectives. Future Microbiol. 2017 Feb;12:141-155.
- Wei Y et al. Thymosin α-1 in cancer therapy: Immunoregulation and potential applications. Int Immunopharmacol. 2023 Apr;117:109744.
- Tuthill C et al. Thymosin alpha 1: past clinical experience and future promise. Ann N Y Acad Sci. 2010 Apr;1194:130-5.
- Goldstein AL. Clinical applications of thymosin alpha-1. Cancer Invest. 1994;12(5):545-7.
- Mao L. Thymosin alpha 1 – Reimagine its broader applications in the immuno-oncology era. Int Immunopharmacol. 2023 Apr;117:109952.
Bi-Test (Cypionate + Propionate)
INDICATIONS AND USAGE:
- Bi-Test is an injectable combination of testosterone cypionate and testosterone propionate used to treat low testosterone levels in men, enhancing muscle mass, strength, and libido.
ADMINISTRATION ROUTE:
- Intramuscular Injection
FORMULATIONS & COST:
- The price sheet below already reflects the 50% HRT member discount.
AMOUNT | COST |
---|---|
25mg-175mg/mL vial (6mL) | $55 |
25mg-175mg/mL vial (12mL) | $80 |
MECHANISM OF ACTION:
- The combination of testosterone cypionate (a long-acting ester) and testosterone propionate (a short-acting ester) provides both immediate and sustained release of testosterone. This dual action helps maintain stable hormone levels and reduces the need for frequent dosing.
COMMON SIDE EFFECTS:
- Common side effects include injection site reactions, increased red blood cell count, mood changes, acne, and gynecomastia. There is also a risk of increased blood pressure and cholesterol changes.
CONTRAINDICATIONS:
- Contraindications include prostate or breast cancer, severe liver or heart conditions, and known hypersensitivity to the components. It should not be used by women, particularly during pregnancy.
MORE INFORMATION:
- FDA Data Safety Sheet for Testosterone Cypionate
- FDA Data Safety Sheet for Testosterone Propionate: Not Available
Nandrolone Decoanate
INDICATIONS AND USAGE:
- Nandrolone Decanoate is an anabolic steroid used to promote muscle growth, support recovery, and alleviate symptoms of muscle wasting in conditions like chronic illness or severe trauma. It is commonly used in the management of anemia associated with kidney disease and for improving bone density in osteoporosis. May be used to minimize muscle tissue catabolism during periods of weight loss.
ADMINISTRATION ROUTE:
- Intramuscular Injection
FORMULATIONS & COST:
- The price sheet below already reflects the 50% HRT member discount.
AMOUNT | COST |
---|---|
200mg/mL vial (6mL) | $100 |
MECHANISM OF ACTION:
- Nandrolone binds to androgen receptors in muscle tissue, stimulating protein synthesis and promoting muscle growth. It also increases red blood cell production, enhancing oxygen delivery to muscles. Its anabolic effects are more pronounced than its androgenic effects, making it suitable for treating conditions that involve muscle loss.
COMMON SIDE EFFECTS:
- Common side effects include water retention, increased blood pressure, acne, and mood changes. Long-term use may lead to cardiovascular issues, liver strain, and hormone imbalances such as suppression of natural testosterone production.
CONTRAINDICATIONS:
- Nandrolone is contraindicated in individuals with prostate or breast cancer, severe heart, liver, or kidney disease, and those who are pregnant. It should not be used by individuals with hypersensitivity to the medication.
MORE INFORMATION:
- NIH Data Safety Sheet for Nandrolone Decanoate
- Haupt HA. Anabolic steroids and growth hormone. Am J Sports Med. 1993 May-Jun;21(3):468-74.
- Patanè et al. Nandrolone Decanoate: Use, Abuse and Side Effects. Medicina (Kaunas). 2020 Nov 11;56(11):606.
- van Marken Lichtenbelt et al. Bodybuilders’ body composition: effect of nandrolone decanoate. Med Sci Sports Exerc. 2004 Mar;36(3):484-9.
- Pan MM et al. Beyond testosterone cypionate: evidence behind the use of nandrolone in male health and wellness. Transl Androl Urol. 2016 Apr;5(2):213-9.
Testosterone + Nandrolone
INDICATIONS AND USAGE:
- This injectable combination is used in hormone replacement therapy for men with low testosterone levels, aiming to enhance muscle mass, improve recovery, and alleviate symptoms of androgen deficiency. It is also used for conditions involving muscle wasting or severe catabolic states.
ADMINISTRATION ROUTE:
- Intramuscular Injection
FORMULATIONS & COST:
- The price sheet below already reflects the 50% HRT member discount.
AMOUNT | COST |
---|---|
100mg-100mg/mL vial (10mL) | $100 |
MECHANISM OF ACTION:
- Combining Testosterone and Nandrolone provides a synergistic effect where Testosterone supports overall androgen levels and sexual function, while Nandrolone primarily promotes muscle growth and recovery by increasing protein synthesis. Together, they enhance muscle mass, strength, and endurance.
COMMON SIDE EFFECTS:
- Common side effects may include water retention, increased blood pressure, acne, and potential suppression of natural testosterone production. There is also a risk of gynecomastia (enlarged breast tissue) due to hormonal imbalances.
CONTRAINDICATIONS:
- Contraindications include prostate cancer, male breast cancer, severe heart, liver, or kidney conditions, and known hypersensitivity to either component. Regular monitoring is necessary to manage potential side effects.
MORE INFORMATION:
- FDA Data Safety Sheet for Testosterone Cypionate
- NIH Data Safety Sheet for Nandrolone Decoanate
Testosterone (Oral)
INDICATIONS AND USAGE:
- Oral testosterone (rapid dissolving tablets and troches) is used in hormone replacement therapy for men with low testosterone levels to restore normal hormone levels and alleviate symptoms such as fatigue, low libido, and muscle loss.
ADMINISTRATION ROUTE:
- Oral Troche
FORMULATIONS & COST:
- The price sheet below already reflects the 50% HRT member discount.
AMOUNT | COST |
---|---|
50mg troche (#30) | $65 |
50mg troche (#90) | $150 |
100mg troche (#30) | $65 |
100mg troche (#90) | $150 |
MECHANISM OF ACTION:
- Testosterone acts as the primary male sex hormone, influencing the development of male secondary sexual characteristics, muscle mass, bone density, and libido. Oral formulations deliver testosterone through the mucous membranes, bypassing the digestive system to avoid first-pass metabolism.
COMMON SIDE EFFECTS:
- Common side effects include headaches, increased red blood cell count, mood changes, and potential liver strain. There may also be a risk of increased blood pressure or gynecomastia (enlarged breast tissue).
CONTRAINDICATIONS:
- Contraindications include prostate cancer, male breast cancer, severe heart or liver disease, and known hypersensitivity to testosterone. It should not be used by women who are pregnant or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet for Testosterone
- Kovac JR et al. Patient satisfaction with testosterone replacement therapies: the reasons behind the choices. J Sex Med. 2014 Feb;11(2):553-62.
- Shoskes JJ et al. Pharmacology of testosterone replacement therapy preparations. Transl Androl Urol. 2016 Dec;5(6):834-843.
- Corona G, Maggi M. The role of testosterone in male sexual function. Rev Endocr Metab Disord. 2022 Dec;23(6):1159-1172.
- Borst SE et al. Cardiovascular risks and elevation of serum DHT vary by route of testosterone administration: a systematic review and meta-analysis. BMC Med. 2014 Nov 27;12:211.
- Skinner JW et al. Muscular responses to testosterone replacement vary by administration route: a systematic review and meta-analysis. J Cachexia Sarcopenia Muscle. 2018 Jun;9(3):465-481.
Testosterone (Topical Cream)
INDICATIONS AND USAGE:
- Testosterone topical cream is used in hormone replacement therapy for men with low testosterone to improve symptoms such as fatigue, decreased libido, and muscle weakness.
ADMINISTRATION ROUTE:
- Topical Cream
FORMULATIONS & COST:
- The price sheet below already reflects the 50% HRT member discount.
AMOUNT | COST |
---|---|
5% (50mg/g) topical cream (30g) | $70 |
5% (50mg/g) topical cream (60g) | $90 |
10% (100mg/g) topical cream (30g) | $75 |
10% (100mg/g) topical cream (60g) | $95 |
20% (200mg/g) topical cream (30g) | $85 |
20% (200mg/g) topical cream (60g) | $105 |
MECHANISM OF ACTION:
- Topical testosterone is absorbed through the skin, providing a steady release of the hormone into the bloodstream to restore normal levels. It mimics the natural diurnal pattern of testosterone production in men.
COMMON SIDE EFFECTS:
- Side effects may include skin irritation at the application site, increased red blood cell count, mood swings, and potential increase in blood pressure. There is also a risk of transferring the medication to others through skin contact.
CONTRAINDICATIONS:
- It is contraindicated in men with prostate or breast cancer and should not be used in women, especially during pregnancy or breastfeeding. Care should be taken to avoid skin contact with others after application.
MORE INFORMATION:
- FDA Data Safety Sheet for Topical Testosterone
- Kovac JR et al. Patient satisfaction with testosterone replacement therapies: the reasons behind the choices. J Sex Med. 2014 Feb;11(2):553-62.
- Shoskes JJ et al. Pharmacology of testosterone replacement therapy preparations. Transl Androl Urol. 2016 Dec;5(6):834-843.
- Corona G, Maggi M. The role of testosterone in male sexual function. Rev Endocr Metab Disord. 2022 Dec;23(6):1159-1172.
- Borst SE et al. Cardiovascular risks and elevation of serum DHT vary by route of testosterone administration: a systematic review and meta-analysis. BMC Med. 2014 Nov 27;12:211.
- Skinner JW et al. Muscular responses to testosterone replacement vary by administration route: a systematic review and meta-analysis. J Cachexia Sarcopenia Muscle. 2018 Jun;9(3):465-481.
Testosterone Cypionate
INDICATIONS AND USAGE:
- Testosterone cypionate is used in hormone replacement therapy to treat men with low testosterone levels, aiming to improve symptoms such as low libido, fatigue, and muscle loss.
ADMINISTRATION ROUTE:
- Intramuscular Injection
FORMULATIONS & COST:
- The price sheet below already reflects the 50% HRT member discount.
AMOUNT | COST |
---|---|
20mg/mL (10mL vial) | $70 |
50mg/mL (5mL vial) | $70 |
100mg/mL (5mL vial) | $70 |
100mg/mL (10mL vial) | $75 |
200mg/mL (5mL vial) | $75 |
200mg/mL (10mL vial) | $80 |
MECHANISM OF ACTION:
- As a long-acting ester of testosterone, testosterone cypionate is absorbed slowly from the injection site, providing a sustained release of the hormone over one to two weeks.
COMMON SIDE EFFECTS:
- Side effects may include increased red blood cell count, water retention, mood changes, acne, and potential suppression of natural testosterone production.
CONTRAINDICATIONS:
- It is contraindicated in men with prostate cancer, breast cancer, or severe heart, liver, or kidney disease. Women, particularly those who are pregnant or breastfeeding, should not use this medication.
MORE INFORMATION:
- FDA Data Safety Sheet for Testosterone Cypionate
- Kovac JR et al. Patient satisfaction with testosterone replacement therapies: the reasons behind the choices. J Sex Med. 2014 Feb;11(2):553-62.
- Shoskes JJ et al. Pharmacology of testosterone replacement therapy preparations. Transl Androl Urol. 2016 Dec;5(6):834-843.
- Corona G, Maggi M. The role of testosterone in male sexual function. Rev Endocr Metab Disord. 2022 Dec;23(6):1159-1172.
- Borst SE et al. Cardiovascular risks and elevation of serum DHT vary by route of testosterone administration: a systematic review and meta-analysis. BMC Med. 2014 Nov 27;12:211.
- Skinner JW et al. Muscular responses to testosterone replacement vary by administration route: a systematic review and meta-analysis. J Cachexia Sarcopenia Muscle. 2018 Jun;9(3):465-481.
Testosterone Cypionate + Anastrozole
INDICATIONS AND USAGE:
- This combination therapy is used in men undergoing testosterone replacement therapy to prevent estrogen-related side effects, such as gynecomastia, by inhibiting the conversion of testosterone to estrogen.
ADMINISTRATION ROUTE:
- Intramuscular Injection
FORMULATIONS & COST:
- The price sheet below already reflects the 50% HRT member discount.
AMOUNT | COST |
---|---|
200mg-0.5mg/ml vial (10mL) | $90 |
200mg-1mg/ml vial (10mL) | $90 |
MECHANISM OF ACTION:
- Testosterone increases androgen levels, while Anastrozole, an aromatase inhibitor, reduces the conversion of testosterone into estrogen, helping to maintain hormonal balance and reduce the risk of estrogenic side effects.
COMMON SIDE EFFECTS:
- Potential side effects include joint pain, fatigue, headaches, increased cholesterol levels, and changes in libido. Testosterone-related side effects such as acne, mood swings, and increased red blood cell count may also occur.
CONTRAINDICATIONS:
- It is contraindicated in men with prostate or breast cancer and in individuals with hypersensitivity to either component. It should not be used by women, particularly those who are pregnant or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet for Testosterone Cypionate
- FDA Data Safety Sheet for Anastrozole
Clomiphene + Resveratrol + B6 + ZMA
INDICATIONS AND USAGE:
- This compounded combination is used to treat men with hypogonadism, aiming to improve testosterone levels, reduce oxidative stress, and support overall hormone balance and energy levels.
ADMINISTRATION ROUTE:
- Oral Capsule
FORMULATIONS & COST:
- The price sheet below already reflects the 50% HRT member discount.
AMOUNT | COST |
---|---|
12.5mg-50mg-10mg-230mg capsule (#30) | $75 |
MECHANISM OF ACTION:
- Clomiphene acts as a selective estrogen receptor modulator (SERM), stimulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which boost testosterone production. Resveratrol provides antioxidant support, Vitamin B6 aids in hormone production and energy metabolism, and ZMA (zinc, magnesium, and Vitamin B6) supports testosterone levels and muscle recovery.
COMMON SIDE EFFECTS:
- Side effects may include headaches, mood swings, nausea, and changes in libido. Clomiphene may cause visual disturbances in some users.
CONTRAINDICATIONS:
- Contraindications include a history of hormone-sensitive cancers or liver disease. It should be used cautiously in men with a history of cardiovascular disease.
MORE INFORMATION:
- FDA Data Safety Sheets: Not available for compounded combinations.
- Huijben M et al. Clomiphene citrate: A potential alternative for testosterone therapy in hypogonadal males. Endocrinol Diabetes Metab. 2023 May;6(3):e416.
- Krzastek SC et al. Non-testosterone management of male hypogonadism: an examination of the existing literature. Transl Androl Urol. 2020 Mar;9(Suppl 2):S160-S170.
- Wu YC et al. Clomiphene Citrate Treatment as an Alternative Therapeutic Approach for Male Hypogonadism: Mechanisms and Clinical Implications. Pharmaceuticals (Basel). 2024 Sep 18;17(9):1233.
- Khodamoradi K et al. Exogenous testosterone replacement therapy versus raising endogenous testosterone levels: current and future prospects. F S Rev. 2021 Jan;2(1):32-42.
Enclomiphene
INDICATIONS AND USAGE:
- Enclomiphene is used to treat secondary hypogonadism in men by stimulating the natural production of testosterone, while preserving fertility.
ADMINISTRATION ROUTE:
- Oral Capsule
FORMULATIONS & COST:
- The price sheet below already reflects the 50% HRT member discount.
AMOUNT | COST |
---|---|
12.5mg capsule (#30) | $90 |
12.5mg capsule (#90) | $220 |
25mg capsule (#30) | $95 |
25mg capsule (#90) | $235 |
50mg capsule (#30) | $140 |
50mg capsule (#90) | $375 |
SUGGESTED PROTOCOL:
- 12.5mg-50mg taken by mouth on an empty stomach once daily
MECHANISM OF ACTION:
- Enclomiphene is a selective estrogen receptor modulator (SERM) that increases the production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn stimulate the testes to produce more testosterone naturally.
COMMON SIDE EFFECTS:
- Common side effects may include headaches, mood changes, nausea, and dizziness. There may also be a risk of increased hematocrit or acne.
CONTRAINDICATIONS:
- Enclomiphene is contraindicated in men with prostate cancer, severe liver disease, or known hypersensitivity to SERMs. It should not be used by women, especially during pregnancy or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available
- Wiehle R et al. Testosterone Restoration by Enclomiphene Citrate in Men with Secondary Hypogonadism: Pharmacodynamics and Pharmacokinetics. BJU Int. 2013 Jul 12;112(8):1188–200.
- Rodriguez KM et al. Enclomiphene Citrate for the Treatment of Secondary Male Hypogonadism. Expert Opin Pharmacother. 2016 Aug;17(11):1561-7.
- Saffati G et al. Safety and Efficacy of Enclomiphene and Clomiphene for Hypogonadal Men. Transl Androl Urol. 2024 Sep 30;13(9):1984-1990.
- Thomas J et al. Efficacy of Clomiphene Citrate Versus Enclomiphene Citrate for Male Infertility Treatment: A Retrospective Study. Cureus. 2023 Jul 6;15(7):e41476.
- Krzastek SC et al. Non-testosterone management of male hypogonadism: an examination of the existing literature. Transl Androl Urol. 2020 Mar;9(Suppl 2):S160-S170.
- Khodamoradi K et al. Exogenous testosterone replacement therapy versus raising endogenous testosterone levels: current and future prospects. F S Rev. 2021 Jan;2(1):32-42.
Gonadorelin
INDICATIONS AND USAGE:
- Gonadorelin is used to stimulate the production of sex hormones, treating conditions like hypogonadism and delayed puberty in men.
- It may help treat or prevent testicular shrinkage in males undergoing testosterone replacement therapy.
- It also may be used to help restart natural testosterone production following cessation of exogenous testosterone or other steroid hormone supplementation (“post-cycle therapy” or PCT).
ADMINISTRATION ROUTE:
- Subcutaneous Injection
- Oral Troche
FORMULATIONS & COST:
- The price sheet below already reflects the 50% HRT member discount.
AMOUNT | COST |
---|---|
400mcg vial (100mcg/mL x 4mL) | $75 |
5mg vial (1mg/mL x 5mL) | $170 |
500mcg troche (#30) | $100 |
SUGGESTED PROTOCOL:
- Subcutaneous injection: inject 100mcg under the skin 2-3x per week
- Oral troche: take one troche by mouth daily
MECHANISM OF ACTION:
- Gonadorelin is a synthetic form of gonadotropin-releasing hormone (GnRH) that stimulates the release of LH and FSH from the pituitary gland, which are essential for testosterone production and spermatogenesis.
COMMON SIDE EFFECTS:
- Potential side effects include headaches, dizziness, nausea, and localized irritation at the injection site.
CONTRAINDICATIONS:
- It is contraindicated in individuals with hormone-sensitive cancers (e.g., prostate cancer) and known hypersensitivity to GnRH analogs.
MORE INFORMATION
- FDA Data Safety Sheet: Not available
- Khodamoradi K et al. Exogenous testosterone replacement therapy versus raising endogenous testosterone levels: current and future prospects. F S Rev. 2021 Jan;2(1):32-42.
KissPeptin-10 Peptide
INDICATIONS AND USAGE:
- Kisspeptin-10 is used to regulate reproductive hormone function and improve fertility in men and women by stimulating the release of gonadotropin hormone releasing hormone, also known as GnRH. It may also have good use in hypoactive sexual desire disorder (HSDD) and has been shown to improve sexual response and function in both men and women.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- The price sheet below already reflects the 50% HRT member discount.
AMOUNT | COST |
---|---|
5mg vial (1mg/mL x 5mL) | $140 |
SUGGESTED PROTOCOL:
- 50mcg-150mcg every 3 days for 30 days
MECHANISM OF ACTION:
- Kisspeptin-10 acts on receptors in the hypothalamus to promote the release of GnRH, which increases the secretion of luteinizing hormone (LH) and follicle stimulating hormone (FSH), leading to enhanced testosterone production.
COMMON SIDE EFFECTS:
- Side effects are typically mild and may include headaches, nausea, or temporary injection site irritation.
CONTRAINDICATIONS:
- Kisspeptin-10 is contraindicated in individuals with hormone-sensitive cancers and those with hypersensitivity to peptide-based therapies.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (research peptide)
- Thurston L et al. Effects of Kisspeptin administration in women with hypoactive sexual desire disorder. JAMA Netw Open. 2022;5(10):e2236131.
- George, JT et al. Kisspeptin-10 is a potent stimulator of LH and increases pulse frequency in men. Journ Clin Endocr & Metab 2011;96(8)1228-1236.
- Patel B et al. The emerging potential of Kisspeptin and Neurokinin B. Endocr Rev. 2023 Jul 20;45(1):30–68.
- Mills et al. Effects of Kisspeptin on sexual brain processing and penile tumescence in men with hypoactive sexual desire disorder. JAMA Netw Open. 2023;6(2):e2254313.
- Clarke et al. Comprehensive Review on Kisspeptin and Its Role in Reproductive Disorders. Endocrinology and Metabolism 2015;30(2):124-141.
- Khodamoradi K et al. Exogenous testosterone replacement therapy versus raising endogenous testosterone levels: current and future prospects. F S Rev. 2021 Jan;2(1):32-42.
Oxandrolone
INDICATIONS AND USAGE:
- Oxandrolone is an oral anabolic steroid used for promoting weight gain following extensive surgery, chronic infection, or severe trauma. It is also indicated for patients suffering from muscle wasting due to conditions like HIV/AIDS and to alleviate bone pain associated with osteoporosis. When taken for short courses at a low dose, it may have a role in promoting muscle sparing during prolonged periods extensive weight loss.
ADMINISTRATION ROUTE:
- Oral Dissolving Troche
FORMULATIONS & COST:
AMOUNT | COST |
---|---|
10mg troche (#30) | Call M.D. |
25mg troche (#30) | Call M.D. |
MECHANISM OF ACTION:
- Oxandrolone enhances protein synthesis, promoting muscle growth and recovery. It increases nitrogen retention in muscle tissue, which supports muscle repair and reduces muscle breakdown. Additionally, it influences bone metabolism by enhancing bone density.
COMMON SIDE EFFECTS:
- Common side effects include liver toxicity, changes in cholesterol levels, acne, and hair loss. It may also cause mood changes and, in high doses, lead to testosterone suppression.
CONTRAINDICATIONS:
- Contraindicated in individuals with prostate or breast cancer, high levels of calcium in the blood (hypercalcemia), and severe liver or kidney disease. It is not recommended for use in women who are pregnant or breastfeeding.
MORE INFORMATION:
- FDA Safety Data Sheet for Oxandrolone: Not Available
- Wu C et al. Novel Uses for the Anabolic Androgenic Steroids Nandrolone and Oxandrolone in the Management of Male Health. Curr Urol Rep. 2016 Oct;17(10):72.
- Berger JR et al. Oxandrolone in AIDS-wasting myopathy. AIDS. 1996 Dec;10(14):1657-62.
- Mavros Y et al. Oxandrolone Augmentation of Resistance Training in Older Women: A Randomized Trial. Med Sci Sports Exerc. 2015 Nov;47(11):2257-67.
Sildenafil (Viagra)
INDICATIONS AND USAGE:
- Sildenafil (the generic form of Viagra) is an oral medication used to treat erectile dysfunction by enhancing blood flow to the penis during sexual stimulation.
ADMINISTRATION ROUTE:
- Oral Troche
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Review the available options on the homepage, then click here to schedule a consultation with Dr. Justl Ellis and sign up or text him at 817-583-8542.
AMOUNT | COST |
---|---|
100mg troche (#30) | $140 |
150mg troche (#30) | $150 |
175mg troche (#30) | $200 |
MECHANISM OF ACTION:
- Sildenafil inhibits phosphodiesterase type 5 (PDE5), an enzyme that degrades cyclic guanosine monophosphate (cGMP). By increasing cGMP levels, Sildenafil promotes relaxation of smooth muscles in the corpus cavernosum, allowing for increased blood flow and an erection.
COMMON SIDE EFFECTS:
- Common side effects include headaches, flushing, indigestion, nasal congestion, and dizziness. It may also cause visual disturbances (e.g., blue-tinged vision).
CONTRAINDICATIONS:
- Sildenafil is contraindicated in individuals taking nitrates or nitric oxide donors, as this can lead to severe hypotension. It should not be used in patients with severe cardiovascular disease or recent history of stroke or heart attack.
MORE INFORMATION:
- FDA Data Safety Sheet for Sildenafil
- Fink HA et al. Sildenafil for male erectile dysfunction: a systematic review and meta-analysis. Arch Intern Med. 2002 Jun 24;162(12):1349-60.
Tadalafil (Cialis)
INDICATIONS AND USAGE:
- Tadalafil (the generic form of Cialis) is an oral medication used to treat erectile dysfunction and is also indicated for benign prostatic hyperplasia (BPH) in some cases.
ADMINISTRATION ROUTE:
- Oral Troche
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Review the available options on the homepage, then click here to schedule a consultation with Dr. Justl Ellis and sign up or text him at 817-583-8542.
AMOUNT | COST |
---|---|
20mg troche (#30) | $140 |
40mg troche (#30) | $150 |
MECHANISM OF ACTION:
- Tadalafil inhibits PDE5, resulting in increased levels of cGMP. This leads to relaxation of smooth muscles in the blood vessels of the penis, promoting enhanced blood flow and an erection. Its longer half-life allows for effects lasting up to 36 hours.
COMMON SIDE EFFECTS:
- Side effects may include headaches, muscle aches, flushing, indigestion, and back pain. It may also cause nasal congestion or dizziness.
CONTRAINDICATIONS:
- Tadalafil is contraindicated in patients taking nitrates or guanylate cyclase stimulators due to the risk of severe hypotension. It should be avoided in individuals with significant cardiovascular conditions.
MORE INFORMATION:
- FDA Data Safety Sheet for Tadalafil
- Coward RM et al. Tadalafil in the treatment of erectile dysfunction. Ther Clin Risk Manag. 2008 Dec;4(6):1315-30.
- Porst H et al. Efficacy of tadalafil for the treatment of erectile dysfunction at 24 and 36 hours after dosing: a randomized controlled trial. Urology. 2003 Jul;62(1):121-5; discussion 125-6.
Oxytocin
INDICATIONS AND USAGE:
- Oxytocin is used to enhance sexual arousal, improve intimacy, and promote social bonding.
ADMINISTRATION ROUTE:
- Oral Troche
- Subcutaneous Injection
- Nasal Spray
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
100IU troche (#15) | $180 |
500IU vial (100IU/mL x 5mL) | $210 |
1000IU nasal spray (200IU/mL x 5mL) | $130 |
SUGGESTED PROTOCOL:
- 25-50IU daily, then an additional 25IU as needed prior to sexual activity
MECHANISM OF ACTION:
- Oxytocin is a naturally occurring hormone that acts on the central nervous system and reproductive organs. It promotes the release of neurotransmitters involved in bonding and sexual arousal, enhancing feelings of closeness and intimacy.
COMMON SIDE EFFECTS:
- Common side effects include headaches, nausea, dizziness, and flushing. It may also cause uterine contractions if used in high doses in pregnant women.
CONTRAINDICATIONS:
- Oxytocin is contraindicated in individuals with known hypersensitivity to the hormone. It should not be used to enhance libido during pregnancy due to its potential to induce labor.
MORE INFORMATION:
- FDA Data Safety Sheet for Oxytocin
- Melis MR, et al. Oxytocin, Erectile Function and Sexual Behavior: Last Discoveries and Possible Advances. Int J Mol Sci. 2021 Sep 26;22(19):10376.
PT-141 (Bremelanotide) Peptide
INDICATIONS AND USAGE:
- PT-141, also known as Bremelanotide, is an FDA-approved peptide medication used to treat hypoactive sexual desire disorder (HSDD) in both men and women by enhancing sexual arousal. It may also have a role in treating erectile dysfunction in males.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
- Nasal Spray
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
50mg nasal spray (10mg/mL x 5mL) | $260 |
20mg vial (10mg/mL x 2mL) | $220 |
SUGGESTED PROTOCOLS:
- 0.75mg-1.75mg as needed 45 minutes before sexual activity. DO NOT exceed 2mg in 72 hours.
MECHANISM OF ACTION:
- PT-141 activates melanocortin receptors in the central nervous system, which are involved in sexual desire and arousal. Unlike other medications for erectile dysfunction, it does not act on the vascular system but rather increases sexual drive by directly stimulating brain pathways.
COMMON SIDE EFFECTS:
- Common side effects include nausea, headaches, flushing, and injection site reactions. Some individuals may experience increased blood pressure or transient darkening of moles or freckles.
CONTRAINDICATIONS:
- PT-141 is contraindicated in individuals with uncontrolled hypertension or cardiovascular disease. It should not be used during pregnancy.
MORE INFORMATION:
- FDA Data Safety Sheet for Bremelanotide
- Diamond et al. Double-blind, placebo-controlled evaluation of the safety, pharmacokinetic properties and pharmacodynamic effects of intranasal PT-141, a melanocortin receptor agonist, in healthy males and patients with mild-to-moderate erectile dysfunction. Int J Impot Res. 2004 Feb;16(1):51-9.
- Molinoff et al. PT-141: a melanocortin agonist for the treatment of sexual dysfunction. Ann N Y Acad Sci. 2003 Jun;994:96-102.
- Safarinejad et al. Salvage of Sildenafil Failures With Bremelanotide: A Randomized, Double-Blind, Placebo Controlled Study. Journal of Urology. 2008 Mar 1;179(3):1066–71.
Tadalafil + PT-141 + Oxytocin
INDICATIONS AND USAGE:
- This combination is used to address multiple aspects of sexual function, including erectile dysfunction, arousal, and emotional bonding, by combining the effects of Tadalafil, PT-141, and Oxytocin.
ADMINISTRATION ROUTE:
- Oral Troche
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
10mg-2mg-50IU troche (#15) | $250 |
MECHANISM OF ACTION:
- Tadalafil enhances blood flow to the penile tissues by inhibiting PDE5, PT-141 stimulates sexual arousal through melanocortin receptors in the brain, and Oxytocin promotes bonding and intimacy by acting on the central nervous system. The combination works to improve both physical and psychological aspects of sexual function.
COMMON SIDE EFFECTS:
- Side effects may include headaches, nausea, flushing, dizziness, and increased heart rate. There may also be localized irritation if taken in other forms, like troches.
CONTRAINDICATIONS:
- This combination is contraindicated in individuals taking nitrates or those with uncontrolled hypertension, cardiovascular conditions, or known hypersensitivity to any of the components. It should not be used during pregnancy.
MORE INFORMATION:
- FDA Data Safety Sheets: Not available for the combination (refer to individual components: Tadalafil, Bremelanotide, and Oxytocin)
- Refer to individual component pages on this website for studies related to each medication.
GHK-Cu Peptide
INDICATIONS AND USAGE:
- GHK-Cu is used in skin care to promote healing, improve skin firmness, and reduce fine lines and wrinkles. It also has applications for treating wounds and reducing inflammation.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
- Topical Cream
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below. Not a member? Review the available options on the homepage, then click here to schedule a consultation with Dr. Justl Ellis and sign up or text him at 817-583-8542.
AMOUNT | COST |
---|---|
50mg vial | $279 |
0.50% cream (30mL) | $299 |
MECHANISM OF ACTION:
- GHK-Cu is a copper peptide that stimulates collagen and glycosaminoglycan synthesis, promotes tissue remodeling, and enhances the production of antioxidant enzymes. It binds to copper, facilitating skin regeneration and repair.
COMMON SIDE EFFECTS:
- Side effects are typically mild and may include temporary skin irritation, redness, or itching at the application site.
CONTRAINDICATIONS:
- GHK-Cu should be used with caution in individuals with known allergies to copper or peptide-based products. It is not recommended during pregnancy or breastfeeding without a doctor’s consultation.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available
- Pickart L et al. The human tri-peptide GHK and tissue remodeling. J Biomater Sci Polym Ed. 2008;19(8):969-988.
- Maquart FX et al. Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex GHK-Cu. FEBS Lett. 1988 Nov;238(2):343-346.
- Pickart L et al. GHK-Cu may prevent oxidative stress in skin by regulating copper and modifying expression of numerous antioxidant genes. Cosmetics. 2015 Jun;2(3):236-247.
- Pickart L et al. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018 Jul 7;19(7):1987.
LL-37 Peptide
INDICATIONS AND USAGE:
- LL-37 is used to enhance skin healing and treat various skin conditions, including chronic wounds, acne, and psoriasis. It is known for its antimicrobial properties.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below. Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
1mg/mL (5mL vial) | $280 |
MECHANISM OF ACTION:
- LL-37 is an antimicrobial peptide that disrupts the membranes of bacteria, viruses, and fungi. It also modulates the immune system, reducing inflammation and promoting wound healing.
COMMON SIDE EFFECTS:
- Potential side effects include localized skin irritation or redness. Long-term safety data are limited due to the peptide’s experimental status.
CONTRAINDICATIONS:
- It should be used cautiously in individuals with autoimmune disorders or known hypersensitivity to peptide products. It is not recommended for use during pregnancy or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (experimental therapy)
- Heilborn JD et al. The cathelicidin anti-microbial peptide LL-37 is involved in re-epithelialization of human skin wounds and is lacking in chronic ulcer epithelium. J Invest Dermatol. 2003 Mar;120(3):379-89.
- Nijnik A, et al. Human Cathelicidin Peptide LL-37 Modulates the Effects of IFN-γ on APCs. J Immunol 2009;183:5788-5798.
- Doss et al. Human defensins and LL-37 in mucosal immunity. J Leukoc Biol. 2010 Jan;87(1):79-92.
- Kahlenberg JM et al. Little peptide, big effects: the role of LL-37 in inflammation and autoimmune disease. J Immunol (2013) 191 (10): 4895–4901.
Melanotan II (Tanning)
INDICATIONS AND USAGE:
- Melanotan II is used for skin tanning by increasing melanin production, potentially reducing the risk of UV-induced skin damage.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
2mg/mL (5mL vial) | $300 |
SUGGESTED PROTOCOL:
- 15 units (0.25mg) subcutaneously daily for 1-2 weeks, then 25 units (0.5mg) subcutaneously twice weekly for maintenance
MECHANISM OF ACTION:
- Melanotan II mimics the action of alpha-melanocyte-stimulating hormone (α-MSH), which stimulates melanocytes in the skin to produce melanin, leading to darker pigmentation. It helps protect the skin against UV radiation.
COMMON SIDE EFFECTS:
- Side effects include nausea, flushing, headaches, and increased pigmentation of moles or freckles. Darkening of existing skin lesions can also occur.
CONTRAINDICATIONS:
- Melanotan II should not be used by individuals with a history of melanoma or skin cancer, as it may darken existing lesions. It is contraindicated in those with known hypersensitivity to the peptide.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (research peptide)
DSIP (Delta Sleep Inducing Peptide)
INDICATIONS AND USAGE:
- DSIP is a peptide used to promote natural sleep patterns and improve sleep quality, especially in individuals with insomnia or irregular sleep cycles.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
9mg vial (3mg/mL x 3mL) | $200 |
SUGGESTED PROTOCOL:
- 100-250mcg nightly 45 minutes before sleep for 4 weeks, then cycling off for 4 weeks, repeating the 8 week cycle as needed.
MECHANISM OF ACTION:
- DSIP is believed to regulate sleep by modulating the activity of neurotransmitters involved in the sleep-wake cycle, including serotonin and melatonin. It also reduces stress-related hormonal activity, potentially aiding in sleep initiation and maintenance.
COMMON SIDE EFFECTS:
- Side effects are generally minimal but may include fatigue, dizziness, or mild headaches. Due to its experimental status, long-term safety data are limited.
CONTRAINDICATIONS:
- DSIP should be avoided in individuals with known hypersensitivity to peptides or those with active neurological disorders. It is not recommended for use during pregnancy or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (experimental peptide therapy)
- Graf MV, Kastin AJ. Delta-sleep-inducing peptide (DSIP): a review. Neurosci Biobehav Rev. 1984 Spring;8(1):83-93.
- Kovalzon et al. Delta sleep-inducing peptide: a still unresolved riddle. Journal of Neurochemistry 2006 Mar;92(2):303-309.
- Schneider-Helmert et al. The influence of synthetic DSIP (delta-sleep-inducing-peptide) on disturbed human sleep. Experientia 37, 913–917 (1981).
- Bes F, Hofman W et al. Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients. A double-blind study. Neuropsychobiology. 1992;26(4):193-7.
BPC-157 Peptide
INDICATIONS AND USAGE:
- BPC-157 is a peptide used to promote healing of various tissues, including muscles, tendons, ligaments, and the gastrointestinal tract. It is often utilized for sports injuries and inflammation control.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
- Intramuscular Injection
- Oral capsules
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
500mcg capsule (#30) | $190 |
10mg vial (2mg/mL x 5mL) | $240 |
20mg vial (4mg/mL x 5mL) | $440 |
SUGGESTED PROTOCOLS:
- 250-500mcg daily for 4-8 weeks
MECHANISM OF ACTION:
- BPC-157 promotes tissue repair and regeneration by enhancing collagen production, angiogenesis (formation of new blood vessels), and modulating growth factors involved in healing. It also reduces inflammation and protects against damage in the gastrointestinal lining.
COMMON SIDE EFFECTS:
- Side effects are typically minimal but may include mild fatigue, nausea, or localized irritation at the injection site.
CONTRAINDICATIONS:
- BPC-157 should be used cautiously in individuals with known allergies to peptides. It is not recommended for use during pregnancy or breastfeeding without consulting a healthcare professional.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (experimental therapy)
- Staresinic et al. Stable Gastric Pentadecapeptide BPC 157 and Striated, Smooth, and Heart Muscle. Biomedicines. 2022; 10(12):3221.
- Seiwerth et al. Stable Gastric Pentadecadpeptide BPC 157 and Wound Healing. Front. Pharmacol., 2021; doi=10.3389
- Gwyer et al. Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing. Cell Tissue Res 377, 153–159 (2019).
- Seiwerth et al. BPC 157 and Standard Angiogenic Growth Factors. Gastrointestinal Tract Healing, Lessons from Tendon, Ligament, Muscle, and Bone Healing. Curr Pharm Desig., 2018; DOI: 10.2174
- Chang et al. The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. J Appl Physiol. 2011 Mar;110(3):774-80.
- Chang et al. Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts. Molecules. 2014;19(11):19066-19077.
- Vukojevic J et al. Pentadecapeptide BPC 157 and the central nervous system. Neural Regen Res. 2022;17(3):482-487. doi:10.4103/1673-5374.320969
- Lee E, Padgett B. Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain. Altern Ther Health Med. 2021;27(4):8-13.
- Sikiric et al. Fistulas Healing. Stable Gastric Pentadecapeptide BPC 157 Therapy. Curr Pharm Des. 2020;26(25):2991-3000.
- Park et al. BPC 157 Rescued NSAID-cytotoxicity Via Stabilizing Intestinal Permeability and Enhancing Cytoprotection. Curr Pharm Des. 2020;26(25):2971-2981.
- Sikiric et al. Toxicity by NSAIDs. Counteraction by stable gastric pentadecapeptide BPC 157. Curr Pharm Des. 2013;19(1):76-83.
BPC-157 + TB-500 (Thymosin Beta-4) Combination
INDICATIONS AND USAGE:
- This combination is used to optimize tissue healing and recovery by leveraging the synergistic effects of BPC-157 and TB-500 (also known as Thymosin Beta-4). It is often used in the treatment of musculoskeletal injuries and inflammation.
ADMINISTRATION ROUTE:
- Oral Capsules
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
500mcg-500mcg capsule (#30) | $310 |
SUGGESTED PROTOCOLS:
- One capsule daily for 4-8 weeks
MECHANISM OF ACTION:
- BPC-157 promotes collagen production and reduces inflammation, while Thymosin Beta-4 facilitates cellular repair and migration. Together, they accelerate the healing process and improve tissue integrity.
COMMON SIDE EFFECTS:
- Potential side effects may include localized irritation, mild fatigue, or nausea. Both peptides are generally well-tolerated, with minimal adverse effects reported.
CONTRAINDICATIONS:
- The combination should not be used in individuals with hypersensitivity to peptide-based treatments or those with severe autoimmune disorders. It is not recommended for use during pregnancy or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (experimental peptide combination)
- See individual component pages on the homepage for comprehensive information and references related to each component
TB-500 (Thymosin Beta-4) Peptide
INDICATIONS AND USAGE:
- TB-500 (also known as Thymosin Beta-4) is used to enhance tissue healing and reduce inflammation, particularly in muscle, tendon, and ligament injuries. It also has potential benefits for wound healing and cardiovascular repair.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
15mg Vial (3mg/mL x 5mL) | $270 |
30mg Vial (6mg/mL x 5mL) | $520 |
SUGGESTED PROTOCOLS:
- 250mcg-500mcg daily for 4-8 weeks
MECHANISM OF ACTION:
- TB-500 promotes cell migration, reduces inflammation, and supports the regeneration of damaged tissues. It regulates actin, a protein involved in cell movement and structure, which is crucial for tissue repair processes.
COMMON SIDE EFFECTS:
- Common side effects may include mild fatigue, headache, or localized injection site reactions. Long-term safety data are limited.
CONTRAINDICATIONS:
- It should be used with caution in individuals with known hypersensitivity to peptides or autoimmune conditions. It is not recommended during pregnancy or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available (experimental therapy)
- Sosne G et al. Biological activities of thymosin beta4 defined by active sites in short peptide sequences. FASEB J. 2010 Jul;24(7):2144-51.
- Sosne G et al. Thymosin beta-4: A novel corneal wound healing and anti-inflammatory agent. Clin Ophthalmol. 2007 Sep;1(3):201-7.
- Malinda KM et al. Thymosin beta-4 accelerates wound healing. J Invest Dermatol. 1999 Sep;113(3):364-8.
- Bock-Marquette I et al. Thymosin beta-4 denotes new directions towards developing prosperous anti-aging regenerative therapies. Int Immunopharmacol. 2023 Mar;116:109741.
- Sosne G et al. Thymosin Beta 4: A Potential Novel Therapy for Neurotrophic Keratopathy, Dry Eye, and Ocular Surface Diseases. Vitam Horm. 2016;102:277-306.
- Bako P et al. Thymosin beta-4 – A potential tool in healing middle ear lesions in adult mammals. Int Immunopharmacol. 2023 Mar;116:109830.
Ascorbic Acid (Vitamin C)
INDICATIONS AND USAGE:
- Ascorbic Acid, also known as Vitamin C, is used to support the immune system, enhance skin health, and act as an antioxidant. It is commonly used for vitamin C deficiency and as an adjunct in the management of chronic illnesses.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
5,000mg vial (500mg/mL x 10mL) | $140 |
MECHANISM OF ACTION:
- Ascorbic acid functions as a potent antioxidant, neutralizing free radicals and protecting cells from oxidative stress. It also plays a key role in collagen synthesis, enhancing skin and connective tissue health, and supports immune defense mechanisms.
COMMON SIDE EFFECTS:
- Common side effects may include gastrointestinal discomfort, such as nausea or diarrhea, especially at high doses.
CONTRAINDICATIONS:
- Contraindications include known hypersensitivity to Ascorbic Acid and conditions like kidney stones, where high doses of Vitamin C may exacerbate symptoms.
MORE INFORMATION:
- FDA Data Safety Sheet for Ascorbic Acid
B-Complex + Lidocaine + Methylfolate
INDICATIONS AND USAGE:
- This combination is used to support nerve health and relieve neuropathic pain, providing essential B vitamins for cellular function and Lidocaine for localized pain relief.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
10mL vial | $160 |
MECHANISM OF ACTION:
- B vitamins, such as B1, B6, and B12, play critical roles in nerve function and energy metabolism, while Methylfolate supports DNA synthesis and repair. Lidocaine acts as a local anesthetic, blocking sodium channels to reduce nerve signal transmission and alleviate pain.
COMMON SIDE EFFECTS:
- Side effects may include mild dizziness, numbness, or localized irritation at the injection site. Rarely, allergic reactions to Lidocaine can occur.
CONTRAINDICATIONS:
- The combination is contraindicated in individuals with hypersensitivity to Lidocaine or any B vitamin component. It should be used cautiously in those with severe liver disease.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available for the combination (refer to individual components: Lidocaine)
B-Complex (+Methyl B12)
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
10mL vial | $140 |
INDICATIONS AND USAGE:
- This combination supports energy metabolism, nerve function, and overall health, often used for B vitamin deficiency or as an adjunct in treating conditions like peripheral neuropathy.
MECHANISM OF ACTION:
- B vitamins play essential roles in cellular energy production and red blood cell formation, while Methylcobalamin (Methyl B12) is a bioavailable form of Vitamin B12, supporting neurological function and DNA synthesis.
COMMON SIDE EFFECTS:
- Side effects are generally rare but may include mild headaches, nausea, or localized injection site reactions.
CONTRAINDICATIONS:
- Contraindications include known allergies to any of the components. Use with caution in individuals with Leber’s disease, a rare genetic eye disorder.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available
Methylcobalamin (B12)
INDICATIONS AND USAGE:
- Methylcobalamin is used for treating Vitamin B12 deficiency and supporting nerve health, energy metabolism, and cognitive function.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
- Intramuscular Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below. Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
1mg/mL (10mL vial) | $70 |
5mg/mL (5mL vial) | $80 |
5mg/mL (10mL vial) | $80 |
10mg/mL (10mL vial) | $140 |
MECHANISM OF ACTION:
- As an active form of Vitamin B12, Methylcobalamin supports the production of red blood cells and helps maintain the myelin sheath that surrounds and protects nerve fibers.
COMMON SIDE EFFECTS:
- Side effects are rare but may include headaches, nausea, or localized injection site reactions.
CONTRAINDICATIONS:
- It is contraindicated in individuals with known hypersensitivity to Vitamin B12 or those with Leber’s disease.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available
Pyridoxine (B6)
INDICATIONS AND USAGE:
- Pyridoxine is used to support nerve function, amino acid metabolism, and red blood cell production. It may also help alleviate symptoms of premenstrual syndrome (PMS) and morning sickness.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
- Intramuscular Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
3,000mg vial (100mg/mL x 30mL) | $70 |
MECHANISM OF ACTION:
- Pyridoxine plays a crucial role in neurotransmitter synthesis and amino acid metabolism, helping maintain nerve health and energy metabolism.
COMMON SIDE EFFECTS:
- Side effects may include mild dizziness or gastrointestinal discomfort. High doses over long periods can cause nerve damage.
CONTRAINDICATIONS:
- Contraindications include known allergies to Pyridoxine. Caution is advised in individuals with Parkinson’s disease who are taking Levodopa.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available
Glutathione
INDICATIONS AND USAGE:
- Glutathione is a powerful antioxidant used to detoxify the body, support the immune system, and reduce oxidative stress. It is also popular for skin brightening.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
- Intramuscular Injection
- Topical Cream
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
1,000mg vial (200mg/mL x 5mL) | $140 |
3,000mg vial (600mg/mL x 5mL) | $270 |
25% topical cream (30g) | $160 |
25% topical cream (60g) | $200 |
MECHANISM OF ACTION:
- Glutathione neutralizes free radicals and detoxifies harmful substances in the liver. It also helps regenerate other antioxidants, such as Vitamin C and E, and supports cellular functions necessary for immune defense.
COMMON SIDE EFFECTS:
- Common side effects may include mild gastrointestinal discomfort, headaches, or allergic reactions if administered intravenously.
CONTRAINDICATIONS:
- Contraindications include known hypersensitivity to Glutathione. Use in individuals with asthma should be cautious, as it may trigger bronchospasm.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available
NAD+ (Nicotinamide Adenine Dinucleotide)
INDICATIONS AND USAGE:
- NAD+ is used to support cellular energy production, DNA repair, and metabolic health, often administered in anti-aging therapies and for conditions like chronic fatigue syndrome.
ADMINISTRATION ROUTE:
- Intramuscular injection
- Subcutaneous injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
2,000mg vial (200mg/mL x 10mL) | $260 |
MECHANISM OF ACTION:
- NAD+ plays a vital role in redox reactions, serving as a coenzyme in cellular respiration processes. It helps convert nutrients into energy and supports mitochondrial function.
COMMON SIDE EFFECTS:
- Side effects may include flushing, headaches, or mild gastrointestinal discomfort.
CONTRAINDICATIONS:
- It should be used cautiously in individuals with known allergies to NAD+ preparations. Safety during pregnancy or breastfeeding is not well established.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available
Vitamin D3
ADMINISTRATION ROUTE:
- Subcutaneous Injection
FORMULATIONS & COST:
- All Recess Rx members receive 50% off the prices listed below.
- Not a member? Click here to schedule a consultation with Dr. Justl Ellis and sign up.
AMOUNT | COST |
---|---|
1,000,000IU vial (100,000IU/mL x 10mL) | $180 |
INDICATIONS AND USAGE:
- Vitamin D3 is used to support bone health, immune function, and calcium absorption. It is commonly prescribed to treat or prevent Vitamin D deficiency.
MECHANISM OF ACTION:
- Vitamin D3 (cholecalciferol) helps maintain blood levels of calcium and phosphorus, promoting bone mineralization. It also modulates immune system activity and supports overall health.
COMMON SIDE EFFECTS:
- Side effects are generally minimal but may include hypercalcemia if taken in excessive doses, leading to symptoms like nausea, vomiting, or kidney stones.
CONTRAINDICATIONS:
- Vitamin D3 is contraindicated in individuals with hypercalcemia or severe kidney disease. Caution is recommended in patients with conditions like sarcoidosis, which can increase sensitivity to Vitamin D.
MORE INFORMATION:
- FDA Data Safety Sheet for Vitamin D3 (Not Available)
Semaglutide + NAD+
INDICATIONS AND USAGE:
- This combination is used for weight management, enhancing weight loss and metabolic health while boosting cellular energy production.
- Patients completing a course of treatment with semaglutide will lose 16% of their body weight, on average, although many patients are able to lose much more if desired.
PRICING MODEL:
- Patients pay a $239 monthly fee for GLP-1 therapy plus a vial charge when additional meds are needed. One 10mg vial charge is paid at sign-up to cover the cost of your initial medication. The first vial will last an average patient approximately three months.
- Semaglutide dosing ranges from 0.5mg/week to 2.5mg/week. Refill vial charges vary depending on how much medication is desired. Patients who maximize lifestyle changes (allowing them to use less medication) will require refills less often and pay less!
- See below for a list of vial charges for the semaglutide / pyridoxine formulation.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
VIAL PRICING:
- This price sheet below already reflects the 50% GLP-1 member discount.
MG / VIAL | COST |
---|---|
1mg vial (1mg/mL x 1mL) | $65 |
3mg vial (1mg/mL x 3mL) | $120 |
8mg vial (2mg/mL x 4mL) | $235 |
10mg vial (5mg/mL x 2mL) | $260 |
MECHANISM OF ACTION:
- Semaglutide, a GLP-1 receptor agonist, promotes weight loss by regulating appetite and slowing gastric emptying, increasing feelings of fullness. NAD+ supports cellular energy metabolism and mitochondrial function, helping reduce fatigue often associated with weight loss.
COMMON SIDE EFFECTS:
- Side effects may include nausea, vomiting, diarrhea, headache, or dizziness. Semaglutide can also cause gastrointestinal discomfort during initial use.
CONTRAINDICATIONS:
- The combination is contraindicated in individuals with a history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2 (MEN 2), or hypersensitivity to any components. Use in pregnancy is not recommended.
MORE INFORMATION
- FDA Data Safety Sheet for Semaglutide
- Texas Health and Human Services Drug Monograph
- Moiz, Areesha et al. Long-Term Efficacy and Safety of Once-Weekly Semaglutide for Weight Loss in Patients Without Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Amer Journ of Card 2023;222:121-130
- John P.H. et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. N Engl J Med 2021;384:989-1002
- Malhotra et al. Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity. N Engl J Med 2024;391:1193-1205
- Jastreboff et al. Tirzepatide Once Weekly for the Treatment of Obesity. N Engl J Med 2022;387:205-216
- Min, T et al. The Role of Tirzepatide, Dual GIP and GLP-1 Receptor Agonist, in the Management of Type 2 Diabetes: The SURPASS Clinical Trials. Diabetes Ther 12, 143–157 (2021).
- Frias, Juan Pablo et al. Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial. The Lancet 2018:392;10160;2180-2193
- Smits et al. Safety of Semaglutide. Front. Endocrinol 2021;12:2021
- Singh G et al.. Wegovy (Semaglutide): A New Weight Loss Drug for Chronic Weight Management. Journal of Investigative Medicine. 2022;70(1):5-13.
- Frederick et al. Cardiovascular and renal outcomes of glucagon-like peptide 1 receptor agonists among patients with and without type 2 diabetes mellitus: A meta-analysis of randomized placebo-controlled trials, Amer J of Prev Card 2024;18;100679
- Frederick et al. Cardiovascular and renal outcomes of glucagon-like peptide 1 receptor agonists among patients with and without type 2 diabetes mellitus: A meta-analysis of randomized placebo-controlled trials, Amer J of Prev Card 2024;18;100679
Semaglutide + Vitamin B6
INDICATIONS AND USAGE:
- This combination is used to support weight loss while boosting metabolism and maintaining nerve function during weight management.
- Patients completing a course of treatment with semaglutide will lose 16% of their body weight, on average, although many patients are able to lose much more if desired.
PRICING MODEL:
- Patients pay a $239 monthly fee for GLP-1 therapy plus a vial charge when additional meds are needed. One 10mg vial charge is paid at sign-up to cover the cost of your initial medication. The first vial will last an average patient approximately three months.
- Semaglutide dosing ranges from 0.5mg/week to 2.5mg/week. Refill vial charges vary depending on how much medication is desired. Patients who maximize lifestyle changes (allowing them to use less medication) will require refills less often and pay less!
- See below for a list of vial charges for the semaglutide / vitamin B6 formulation.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
VIAL PRICING:
- This price sheet below already reflects the 50% GLP-1 member discount.
VIAL SIZE | COST |
---|---|
1mg vial (1mg/mL x 1mL) | $85 |
2mg vial (2mg/mL x 1mL) | $100 |
4mg vial (4mg/mL x 1mL) | $135 |
8mg vial (4mg/mL x 2mL) | $155 |
10mg vial (5mg/mL x 2mL) | $180 |
12.5mg vial (2.5mg/mL x 5mL) | $220 |
30mg vial (5mg/mL x 6mL) | $470 |
MECHANISM OF ACTION:
- Semaglutide regulates appetite through GLP-1 receptor activation, while Pyridoxine (Vitamin B6) supports metabolism and nerve health, helping alleviate fatigue and improve overall well-being during weight loss.
COMMON SIDE EFFECTS:
- Side effects may include gastrointestinal discomfort, headache, or dizziness. Pyridoxine is generally well tolerated but may cause mild nausea in some individuals.
CONTRAINDICATIONS:
- The combination is contraindicated in individuals with a history of medullary thyroid carcinoma, MEN 2, or known allergies to any components. It should not be used during pregnancy.
MORE INFORMATION
- FDA Data Safety Sheet for Semaglutide
- Texas Health and Human Services Drug Monograph
- Moiz, Areesha et al. Long-Term Efficacy and Safety of Once-Weekly Semaglutide for Weight Loss in Patients Without Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Amer Journ of Card 2023;222:121-130
- John P.H. et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. N Engl J Med 2021;384:989-1002
- Malhotra et al. Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity. N Engl J Med 2024;391:1193-1205
- Jastreboff et al. Tirzepatide Once Weekly for the Treatment of Obesity. N Engl J Med 2022;387:205-216
- Min, T et al. The Role of Tirzepatide, Dual GIP and GLP-1 Receptor Agonist, in the Management of Type 2 Diabetes: The SURPASS Clinical Trials. Diabetes Ther 12, 143–157 (2021).
- Frias, Juan Pablo et al. Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial. The Lancet 2018:392;10160;2180-2193
- Smits et al. Safety of Semaglutide. Front. Endocrinol 2021;12:2021
- Singh G et al.. Wegovy (Semaglutide): A New Weight Loss Drug for Chronic Weight Management. Journal of Investigative Medicine. 2022;70(1):5-13.
- Frederick et al. Cardiovascular and renal outcomes of glucagon-like peptide 1 receptor agonists among patients with and without type 2 diabetes mellitus: A meta-analysis of randomized placebo-controlled trials, Amer J of Prev Card 2024;18;100679
- Frederick et al. Cardiovascular and renal outcomes of glucagon-like peptide 1 receptor agonists among patients with and without type 2 diabetes mellitus: A meta-analysis of randomized placebo-controlled trials, Amer J of Prev Card 2024;18;100679
Semaglutide + Vitamin B12
INDICATIONS AND USAGE:
- An oral combination used for weight loss and energy support, especially in individuals with Vitamin B12 deficiency or increased requirements.
ADMINISTRATION ROUTE:
- Rapid Dissolving Oral Strip (RDOS)
FORMULATIONS & COST:
- This price sheet below already reflects the 50% GLP-1 member discount.
AMOUNT | COST |
---|---|
0.5mg RDOS (#30) | $540 |
0.5mg RDOS (#4) | $38 |
MECHANISM OF ACTION:
- Semaglutide reduces appetite by acting as a GLP-1 receptor agonist, while Vitamin B12 supports red blood cell production and energy metabolism, improving fatigue and preventing deficiency during weight loss.
COMMON SIDE EFFECTS:
- Common side effects include gastrointestinal symptoms, dizziness, and fatigue. Vitamin B12 is typically well tolerated but may cause mild headaches in some individuals.
CONTRAINDICATIONS:
- This combination is contraindicated in patients with a history of medullary thyroid carcinoma, MEN 2, or allergies to any components. It is not recommended during pregnancy.
MORE INFORMATION:
- FDA Data Safety Sheet for Semaglutide
- Meier J. Efficacy of Semaglutide in a Subcutaneous and an Oral Formulation. Front. Endocrinol. 2021;12
- Gallwitz et al. Clinical Perspectives on the Use of Subcutaneous and Oral Formulations of Semaglutide. Front. Endocrinol. 2021;12
- Frederick et al. Cardiovascular and renal outcomes of glucagon-like peptide 1 receptor agonists among patients with and without type 2 diabetes mellitus: A meta-analysis of randomized placebo-controlled trials, Amer J of Prev Card 2024;18;100679
Semaglutide + Vitamin B6
INDICATIONS AND USAGE:
- This oral combination is used to support weight loss while boosting metabolism and maintaining nerve function during weight management.
- Oral absorpation of semaglutide is less predictable than the injected formulations and should be reserved for those patients who are unable to tolerate weekly injections.
ADMINISTRATION ROUTE:
- Rapid Dissolving Tablet (RDT)
FORMULATIONS & COST:
- This price sheet below already reflects the 50% GLP-1 member discount.
AMOUNT | COST |
---|---|
0.6mg RDT (8 wk starter pack) | $310 |
3.6mg RDT (4 wk maint. pack) | $375 |
SUGGESTED PROTOCOL:
- Initiation: Dissolve 1 tablet of 0.6mg semaglutide under the tongue twice weekly for 2 weeks, then increase by 1 tablet for each subsequent 2 week period through week 8.
- Maintenance: dissolve 1 tablet of 3.6mg semaglutide under the tongue twice weekly for 4 weeks.
MECHANISM OF ACTION:
- Semaglutide regulates appetite through GLP-1 receptor activation, while Pyridoxine (Vitamin B6) supports metabolism and nerve health, helping alleviate fatigue and improve overall well-being during weight loss.
COMMON SIDE EFFECTS:
- Side effects may include gastrointestinal discomfort, headache, or dizziness. Pyridoxine is generally well tolerated but may cause mild nausea in some individuals.
CONTRAINDICATIONS:
- The combination is contraindicated in individuals with a history of medullary thyroid carcinoma, MEN 2, or known allergies to any components. It should not be used during pregnancy.
MORE INFORMATION:
- FDA Data Safety Sheet for Semaglutide
- Meier J. Efficacy of Semaglutide in a Subcutaneous and an Oral Formulation. Front. Endocrinol. 2021;12
- Gallwitz et al. Clinical Perspectives on the Use of Subcutaneous and Oral Formulations of Semaglutide. Front. Endocrinol. 2021;12
- Frederick et al. Cardiovascular and renal outcomes of glucagon-like peptide 1 receptor agonists among patients with and without type 2 diabetes mellitus: A meta-analysis of randomized placebo-controlled trials, Amer J of Prev Card 2024;18;100679
Tirzepatide + Levocarnitine
INDICATIONS AND USAGE:
- This combination is used to enhance weight loss by regulating appetite and increasing fat metabolism.
- Patients completing a course of treatment with tirzepatide will lose 23% of their body weight, on average, although many patients are able to lose much more if desired.
PRICING MODEL:
- Patients pay a $239 monthly fee for GLP-1 therapy plus a vial charge when additional meds are needed. One 60mg vial charge is paid at sign-up to cover the cost of your initial medication. The first vial will last an average patient approximately three months.
- Tirzepatide dosing ranges from 3mg/week to 15mg/week. Refill vial charges vary depending on how much medication is desired. Patients who maximize lifestyle changes (allowing them to use less medication) will require refills less often and pay less!
- See below for a list of vial charges for the tirzepatide / levocarnitine formulation.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
VIAL PRICING
- This price sheet below already reflects the 50% GLP-1 member discount.
DOSE | COST |
---|---|
10mg vial (5mg/mL x 2mL) | $150 |
30mg vial (15mg/mL x 2mL) | $360 |
60mg vial (15mg/mL x 4mL) | $530 |
MECHANISM OF ACTION:
- Tirzepatide is a dual GLP-1 and GIP receptor agonist that helps promote weight loss by increasing satiety, while levocarnitine facilitates the transport of fatty acids into mitochondria for energy production, enhancing fat oxidation. Levocarnitine may also contribute to muscle sparing during prolonged periods of weight loss.
COMMON SIDE EFFECTS:
- Common side effects include gastrointestinal discomfort, headache, or dizziness. Levocarnitine may cause a “fishy” body odor in some individuals.
CONTRAINDICATIONS:
- The combination is contraindicated in individuals with known allergies to any components or those with uncontrolled thyroid disorders. It should not be used during pregnancy.
MORE INFORMATION:
- FDA Data Safety Sheet for Tirzepatide
- Malhotra et al. Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity. N Engl J Med 2024;391:1193-1205
- Jastreboff et al. Tirzepatide Once Weekly for the Treatment of Obesity. N Engl J Med 2022;387:205-216
- Min, T et al. The Role of Tirzepatide, Dual GIP and GLP-1 Receptor Agonist, in the Management of Type 2 Diabetes: The SURPASS Clinical Trials. Diabetes Ther 12, 143–157 (2021).
- Frias, Juan Pablo et al. Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial. The Lancet 2018:392;10160;2180-2193
- Frederick et al. Cardiovascular and renal outcomes of glucagon-like peptide 1 receptor agonists among patients with and without type 2 diabetes mellitus: A meta-analysis of randomized placebo-controlled trials, Amer J of Prev Card 2024;18;100679
Tirzepatide + Vitamin B6
INDICATIONS AND USAGE:
- This combination is used for weight loss support and to enhance energy metabolism and nerve health.
- Patients completing a course of treatment with tirzepatide will lose 23% of their body weight, on average, although many patients are able to lose much more if desired.
PRICING MODEL:
- Patients pay a $239 monthly fee for GLP-1 therapy plus a vial charge when additional meds are needed. One 60mg vial charge is paid at sign-up to cover the cost of your initial medication. The first vial will last an average patient approximately three months.
- Tirzepatide dosing ranges from 3mg/week to 15mg/week. Refill vial charges vary depending on how much medication is desired. Patients who maximize lifestyle changes (allowing them to use less medication) will require refills less often and pay less!
- See below for a list of vial charges for the tirzepatide / B6 formulation.
ADMINISTRATION ROUTE:
- Subcutaneous Injection
VIAL PRICING:
- This price sheet below already reflects the 50% GLP-1 member discount.
VIAL SIZE | COST |
---|---|
10mg vial (10mg/mL x 1mL) | $190 |
20mg vial (20mg/mL x 1mL) | $220 |
30mg vial (10mg/mL x 3mL) | $230 |
40mg vial (20mg/mL x 2mL) | $365 |
60mg vial (30mg/mL x 2mL) | $420 |
180mg vial (30mg/mL x 6mL) | $1120 |
MECHANISM OF ACTION:
- Tirzepatide aids in weight reduction by stimulating GLP-1 and GIP receptors, leading to decreased appetite and improved insulin sensitivity. Pyridoxine supports nerve function and helps mitigate fatigue during weight loss.
COMMON SIDE EFFECTS:
- Potential side effects include gastrointestinal discomfort, headache, or mild dizziness. Pyridoxine is well tolerated but may cause mild side effects like nausea.
CONTRAINDICATIONS:
- The combination is contraindicated in individuals with medullary thyroid carcinoma, MEN 2, or known hypersensitivity to any components. Use in pregnancy is not recommended.
MORE INFORMATION:
- FDA Data Safety Sheet for Tirzepatide
- Malhotra et al. Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity. N Engl J Med 2024;391:1193-1205
- Jastreboff et al. Tirzepatide Once Weekly for the Treatment of Obesity. N Engl J Med 2022;387:205-216
- Min, T et al. The Role of Tirzepatide, Dual GIP and GLP-1 Receptor Agonist, in the Management of Type 2 Diabetes: The SURPASS Clinical Trials. Diabetes Ther 12, 143–157 (2021).
- Frias, Juan Pablo et al. Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial. The Lancet 2018:392;10160;2180-2193
- Frederick et al. Cardiovascular and renal outcomes of glucagon-like peptide 1 receptor agonists among patients with and without type 2 diabetes mellitus: A meta-analysis of randomized placebo-controlled trials, Amer J of Prev Card 2024;18;100679
Testosterone Cypionate
INDICATIONS AND USAGE:
- Testosterone Cypionate is used in women for hormone replacement therapy to improve libido, energy levels, and muscle mass, particularly in cases of androgen deficiency.
ADMINISTRATION ROUTE:
- Intramuscular Injection
- Subcutaneous Injection
FORMULATIONS & COST:
- Note: the price sheet below already reflects the 50% discount for HRT members.
AMOUNT | COST |
---|---|
10mg/mL (5mL vial) | $60 |
20mg/mL (1mL vial) | $50 |
20mg/mL (3mL vial) | $55 |
20mg/mL (10mL vial) | $70 |
40mg/mL (1mL vial) | $20 |
40mg/mL (6mL vial) | $65 |
40mg/mL (10mL vial) | $75 |
50mg/mL (1mL vial) | $50 |
50mg/mL (3mL vial) | $55 |
50mg/mL (5mL vial) | $70 |
MECHANISM OF ACTION:
- Testosterone supplementation helps restore androgen levels, supporting sexual health, muscle strength, and overall vitality.
COMMON SIDE EFFECTS:
- Side effects may include increased body hair, acne, mood changes, or changes in voice. High doses may exacerbate hormone-sensitive conditions.
CONTRAINDICATIONS:
- It is contraindicated in women with hormone-sensitive cancers, severe liver disease, or cardiovascular conditions.
MORE INFORMATION:
- FDA Data Safety Sheet for Testosterone Cypionate
- Davis SR et al. Efficacy and safety of testosterone in the management of hypoactive sexual desire disorder in postmenopausal women. J Sex Med. 2012 Apr;9(4):1134-48.
- Dunsmoor-Su R et al. Testosterone Therapy in Women: A Clinical Challenge. Obstet Gynecol. 2021 Nov 1;138(5):809-812.
- Davis SR et al. Testosterone in women–the clinical significance. Lancet Diabetes Endocrinol. 2015 Dec;3(12):980-92.
- Glaser R et al. Testosterone therapy in women: myths and misconceptions. Maturitas. 2013 Mar;74(3):230-4.
- Islam RM et al. Effects of testosterone therapy for women: a systematic review and meta-analysis protocol. Syst Rev. 2019 Jan 11;8(1):19.
Testosterone (Oral)
INDICATIONS AND USAGE:
- Testosterone tablets or troches are used in hormone replacement therapy to improve symptoms associated with low testosterone in women, such as low libido, fatigue, and decreased muscle mass.
ADMINISTRATION ROUTE:
- Oral Troche (OT)
FORMULATIONS & COST:
- The price sheet below already reflects the 50% HRT member discount.
AMOUNT | COST |
---|---|
2mg troche (#30) | $65 |
2mg troche (#60) | $85 |
5mg troche (#30) | $65 |
5mg troche (#60) | $85 |
10mg troche (#30) | $65 |
10mg troche (#60) | $85 |
20mg troche (#30) | $65 |
20mg troche (#60) | $85 |
MECHANISM OF ACTION:
- Orally or sublingually administered Testosterone increases androgen levels, which supports sexual health, energy, and muscle maintenance. It helps alleviate symptoms associated with low androgen levels in women.
COMMON SIDE EFFECTS:
- Side effects may include acne, voice changes, mood swings, increased body hair growth, or fluid retention. In some cases, it may cause changes in cholesterol levels.
CONTRAINDICATIONS:
- Contraindications include a history of hormone-sensitive cancers (e.g., breast cancer), severe liver or cardiovascular disease, and known hypersensitivity to testosterone. It should not be used during pregnancy.
MORE INFORMATION:
- FDA Data Safety Sheet for Testosterone
- Uloko, M., Rahman, F., Puri, L.I. et al. The clinical management of testosterone replacement therapy in postmenopausal women with hypoactive sexual desire disorder: a review. Int J Impot Res 34, 635–641 (2022).
- Elraiyah T et al. The benefits and harms of systemic testosterone therapy in postmenopausal women with normal adrenal function: a systematic review and meta-analysis. J Clin Endocrinol Metab. 2014 Oct 3;99(10):3543-3550.
- Traish et al. Androgen therapy in women with testosterone insufficiency: looking back and looking ahead. J Androgens: Clin Res and Ther. 2022 Feb;3(1).
- Islam et al. Safety and efficacy of testosterone for women: a systematic review and meta-analysis of randomised controlled trial data. Lancet Diabetes Endocrinol. 2019 Oct;7(10):754-766.
Testosterone (Topical Cream)
INDICATIONS AND USAGE:
- Testosterone topical cream is used for hormone replacement in women with low testosterone levels, aiming to improve libido, energy, mood, and muscle strength.
ADMINISTRATION ROUTE:
- Topical Cream
FORMULATIONS & COST:
- The price sheet below already reflects the 50% HRT member discount.
AMOUNT | COST |
---|---|
3% (30mg/g) cream (30g) | $65 |
3% (30mg/g) cream (60g) | $85 |
4% (40mg/g) cream (30g) | $65 |
4% (40mg/g) cream (60g) | $85 |
MECHANISM OF ACTION:
- The topical application of Testosterone is absorbed through the skin, allowing for a gradual release of the hormone into the bloodstream. This supports increased androgen levels while providing a more stable dosing method.
COMMON SIDE EFFECTS:
- Common side effects include localized skin irritation, acne, increased hair growth, mood changes, and potential changes in voice. There may also be a risk of transferring the hormone to others through skin contact.
CONTRAINDICATIONS:
- It is contraindicated in individuals with hormone-sensitive cancers, severe liver disease, and cardiovascular conditions. It should not be used during pregnancy or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available for topical use (refer to Testosterone)
- Davis SR et al. Efficacy and safety of transdermal testosterone in postmenopausal women with low libido: A randomized, placebo-controlled trial. Menopause. 2006 May;13(5): 770-779.
- El-Hage et al. A double-blind, randomized, placebo-controlled trial of the effect of testosterone cream on the sexual motivation of menopausal hysterectomized women with hypoactive sexual desire disorder. Climacteric. 2007 Aug;10(4):335-43.
- Ganesan K et al. Transdermal Testosterone in Female Hypoactive Sexual Desire Disorder: A Rapid Qualitative Systematic Review Using Grading of Recommendations Assessment, Development and Evaluation. Cureus. 2018 Mar 31;10(3):e2401..
- Kingsberg SA et al. Testosterone treatment for hypoactive sexual desire disorder in postmenopausal women: A review. Fertil Steril. 2010 Aug;94(1):103-108.
DHEA
INDICATIONS AND USAGE:
- DHEA (Dehydroepiandrosterone) is used to support hormone balance, energy, and overall well-being, particularly in aging women experiencing symptoms of low androgens.
ADMINISTRATION ROUTE:
- Oral Capsule
FORMULATIONS & COST:
- The price sheet below already reflects the 50% discount for HRT members.
AMOUNT | COST |
---|---|
10mg capsule (#30) | $65 |
10mg capsule (#60) | $75 |
MECHANISM OF ACTION:
- DHEA is a hormone precursor that the body converts into androgens and estrogens. Supplementation helps increase levels of these sex hormones, potentially improving mood, libido, and energy.
COMMON SIDE EFFECTS:
- Common side effects may include acne, hair loss, mood changes, and increased body hair. High doses may exacerbate hormone-sensitive conditions.
CONTRAINDICATIONS:
- Contraindications include hormone-sensitive cancers, liver disease, and uncontrolled adrenal disorders. It should not be used during pregnancy or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available
- Morales AJ et al. Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age. J Clin Endocrinol Metab. 1994 Jun;78(6):1360-1367.
- Baulieu EE et al. Dehydroepiandrosterone (DHEA): A fountain of youth? J Clin Endocrinol Metab. 1996 Aug;81(9):3147-3151.
- Arlt W et al. Dehydroepiandrosterone replacement in women with adrenal insufficiency. N Engl J Med. 1999 Sep;341(14):1013-1020.
- Villareal et al. Effects of DHEA replacement on bone mineral density and body composition in elderly women and men. Clin Endocrinol (Oxf). 2000 Nov;53(5):561-8.
DHEA + Pregnenolone
INDICATIONS AND USAGE:
- This oral combination is used to support hormonal balance, cognitive function, and anti-aging in women experiencing symptoms of declining sex hormones.
ADMINISTRATION ROUTE:
- Oral Capsule
FORMULATIONS & COST:
- The price sheet below already reflects the 50% member discount.
AMOUNT | COST |
---|---|
10mg-15mg capsule (#30) | $65 |
10mg-15mg capsule (#60) | $75 |
MECHANISM OF ACTION:
- DHEA serves as a precursor to androgens and estrogens, while Pregnenolone, another precursor hormone, supports the production of various steroids, including progesterone and cortisol. Together, they help maintain overall hormonal balance.
COMMON SIDE EFFECTS:
- Possible side effects include acne, changes in hair growth, mood alterations, and fatigue. Higher doses may increase the risk of hormone-sensitive conditions.
CONTRAINDICATIONS:
- Contraindications include hormone-sensitive cancers, uncontrolled adrenal disorders, and severe liver disease. It should be avoided during pregnancy or breastfeeding.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available
- Morales AJ et al. Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age. J Clin Endocrinol Metab. 1994 Jun;78(6):1360-1367.
- Baulieu EE et al. Dehydroepiandrosterone (DHEA): A fountain of youth? J Clin Endocrinol Metab. 1996 Aug;81(9):3147-3151.
- Arlt W et al. Dehydroepiandrosterone replacement in women with adrenal insufficiency. N Engl J Med. 1999 Sep;341(14):1013-1020.
- Villareal et al. Effects of DHEA replacement on bone mineral density and body composition in elderly women and men. Clin Endocrinol (Oxf). 2000 Nov;53(5):561-8.
Progesterone (Oral)
INDICATIONS AND USAGE:
- Oral Progesterone is used to balance estrogen therapy in hormone replacement, reduce the risk of endometrial hyperplasia, and alleviate symptoms of hormonal imbalance.
ADMINISTRATION ROUTE:
- Oral Capsules (OC)
- Oral Troches (OT)
FORMULATIONS & COST:
- The price sheet below already reflects the 50% member discount.
AMOUNT | COST |
---|---|
50mg OC (#30) | $58 |
50mg OC (#60) | $67 |
100mg OC (#30) | $62 |
100mg OC (#60) | $72 |
200mg OC (#30) | $65 |
200mg OC (#60) | $77 |
200mg OT (#30) | $77 |
200mg OT (#60) | $116 |
MECHANISM OF ACTION:
- Progesterone stabilizes the uterine lining and counteracts the effects of estrogen on the endometrium. It also supports mood regulation and sleep quality.
COMMON SIDE EFFECTS:
- Common side effects may include dizziness, fatigue, mood changes, and headaches. It may also cause gastrointestinal discomfort.
CONTRAINDICATIONS:
- Contraindications include a history of hormone-sensitive cancers, liver disease, or unexplained vaginal bleeding. It should not be used during pregnancy.
MORE INFORMATION:
- FDA Data Safety Sheet for Progesterone
- Stute P et al. The impact of micronized progesterone on the endometrium: a systematic review. Climacteric. 2016 Aug;19(4):316-28.
- Ruan et al. Systemic progesterone therapy—Oral, vaginal, injections and even transdermal? Maturitas. 2014 Nov;79(3):248-255
- Memi E et al. Diagnostic and therapeutic use of oral micronized progesterone in endocrinology. Rev Endocr Metab Disord. 2024 Aug;25(4):751-772.
Bi-Estrogen (Estriol + Estradiol) Cream
INDICATIONS AND USAGE:
- Bi-Estrogen cream is used in hormone replacement therapy for menopausal women to alleviate symptoms such as hot flashes, vaginal dryness, and mood changes. It combines two forms of estrogen to mimic natural hormonal balance.
ADMINISTRATION ROUTE:
- Topical Cream
FORMULATIONS & COST:
- The price sheet below already reflects the 50% HRT member discount.
AMOUNT | COST |
---|---|
0.2% (2mg/g) cream (30gm) | $65 |
0.2% (2mg/g) cream (60gm) | $75 |
0.5% (5mg/g) cream (30gm) | $65 |
0.5% (5mg/g) cream (60gm) | $75 |
MECHANISM OF ACTION:
- Estradiol is a potent estrogen that alleviates severe menopausal symptoms, while Estriol, a weaker estrogen, helps balance the formulation and reduce the risk of side effects associated with stronger estrogen therapies. Together, they help replenish declining hormone levels.
COMMON SIDE EFFECTS:
- Common side effects may include breast tenderness, headaches, nausea, and localized irritation at the application site. Long-term use may increase the risk of blood clots or certain cancers.
CONTRAINDICATIONS:
- Contraindications include a history of estrogen-sensitive cancers, liver disease, or a history of thromboembolic disorders. It should not be used during pregnancy.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available for combination (refer to individual components: Estradiol and Estriol)
- Cirigliano M et al. Bioidentical hormone therapy: a review of the evidence. J Womens Health (Larchmt). 2007 Jun;16(5):600-31. .
- Mattison, et al. The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use. 2020 The National Academies Press. https://doi.org/10.17226/2579.
Bi-Estrogen (Estriol + Estrodiol) + Progesterone + Testosterone
INDICATIONS AND USAGE:
- This comprehensive hormone replacement cream is used for treating menopausal symptoms while balancing estrogen, progesterone, and testosterone levels to support overall well-being.
ADMINISTRATION ROUTE:
- Topical Cream
FORMULATIONS & COST:
- The price sheet below already reflects the 50% HRT member discount.
AMOUNT | COST |
---|---|
1mg-100mg-2mg/g (30g) | $65 |
1mg-100mg-2mg/g (60g) | $80 |
2mg-200mg-5mg/g (30g) | $75 |
2mg-200mg-5mg/g (60g) | $85 |
MECHANISM OF ACTION:
- Estradiol and Estriol provide estrogenic effects to alleviate menopausal symptoms, while Progesterone protects the uterine lining from estrogen stimulation. Testosterone is added to support libido, energy, and muscle mass.
COMMON SIDE EFFECTS:
- Side effects may include breast tenderness, mood swings, headaches, or skin irritation. There is also an increased risk of blood clots and certain cancers with long-term use.
CONTRAINDICATIONS:
- Contraindications include a history of hormone-sensitive cancers, liver disease, and thromboembolic disorders. It is not recommended during pregnancy.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available for combination (refer to individual components: Estradiol, Estriol, Progesterone, and Testosterone)
- Cirigliano M et al. Bioidentical hormone therapy: a review of the evidence. J Womens Health (Larchmt). 2007 Jun;16(5):600-31. .
- Mattison, et al. The Clinical Utility of Compounded Bioidentical Hormone Theraphy: A Review of Safety, Effectiveness, and Use. 2020 The National Academies Press. https://doi.org/10.17226/2579.
Estradiol Cream
INDICATIONS AND USAGE:
- Estradiol cream is used in hormone replacement therapy to treat menopausal symptoms, particularly vaginal atrophy and dryness.
ADMINISTRATION ROUTE:
- Topical Cream
FORMULATIONS & COST:
- The price sheet below already reflects the 50% HRT member discount.
AMOUNT | COST |
---|---|
0.01% (0.1mg/g) cream (30g) | $65 |
0.01% (0.1mg/g) cream (60g) | $75 |
0.1% (1mg/g) cream (30g) | $65 |
0.1% (1mg/g) cream (60g) | $75 |
1% (10mg/g) cream (30g) | $65 |
1% (10mg/g) cream (60g) | $80 |
MECHANISM OF ACTION:
- Estradiol replenishes declining estrogen levels in the body, providing relief from symptoms associated with menopause. It helps maintain the health of the vaginal mucosa and supports bone density.
COMMON SIDE EFFECTS:
- Side effects may include breast tenderness, nausea, headaches, or localized irritation. Long-term use may increase the risk of blood clots or certain cancers.
CONTRAINDICATIONS:
- It is contraindicated in women with a history of estrogen-sensitive cancers, liver disease, or thromboembolic disorders. It should not be used during pregnancy.
MORE INFORMATION:
- FDA Data Safety Sheet for Estradiol Topical Gel
- FDA Data Safety Sheet for Estradiol Topical Cream
- FDA Data Safety Sheet for Estradiol Topical Emulsion
- Santen RJ et al, Constantine GD. Systemic estradiol levels with low-dose vaginal estrogens. Menopause. 2020 Mar;27(3):361-370.
- Castelo-Branco et al. Clinical efficacy of estradiol transdermal system in the treatment of hot flashes in postmenopausal women. Research and Reports in Transdermal Drug Delivery. 2014;3:1-8
Estriol Cream
INDICATIONS AND USAGE:
- Estriol cream is used to treat symptoms of vaginal dryness and mild menopausal symptoms, providing a milder estrogenic effect than other forms of estrogen therapy.
ADMINISTRATION ROUTE:
- Topical Cream
FORMULATIONS & COST:
- The price sheet below already reflects the 50% HRT member discount.
AMOUNT | COST |
---|---|
0.01% (0.1mg/g) cream (30g) | $65 |
0.01% (0.1mg/g) cream (60g) | $75 |
0.1% (1mg/g) cream (30g) | $65 |
0.1% (1mg/g) cream (60g) | $75 |
1% (10mg/g) cream (30g) | $65 |
1% (10mg/g) cream (60g) | $75 |
MECHANISM OF ACTION:
- Estriol is a weaker estrogen that helps maintain the vaginal mucosa and alleviate mild menopausal symptoms by binding to estrogen receptors and promoting tissue health.
COMMON SIDE EFFECTS:
- Side effects may include localized irritation, breast tenderness, or headaches. The risk of side effects is generally lower compared to stronger estrogens.
CONTRAINDICATIONS:
- Contraindications include a history of estrogen-sensitive cancers, liver disease, or thromboembolic disorders. It should not be used during pregnancy.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available
- Santen RJ et al, Constantine GD. Systemic estradiol levels with low-dose vaginal estrogens. Menopause. 2020 Mar;27(3):361-370.
- Castelo-Branco et al. Clinical efficacy of estradiol transdermal system in the treatment of hot flashes in postmenopausal women. Research and Reports in Transdermal Drug Delivery. 2014;3:1-8
Progesterone Cream
INDICATIONS AND USAGE:
- Topical progesterone is used to support hormone balance in menopausal women and reduce symptoms like hot flashes and mood swings.
ADMINISTRATION ROUTE:
- Topical Cream
FORMULATIONS & COST:
- The price sheet below already reflects the 50% HRT member discount.
AMOUNT | COST |
---|---|
5% (50mg/g) cream (30gm) | $65 |
5% (50mg/g) cream (60gm) | $75 |
10% (100mg/g) cream (30gm) | $65 |
10% (100mg/g) cream (60gm) | $75 |
20% (200mg/g) cream (30gm) | $65 |
20% (200mg/g) cream (60gm) | $80 |
MECHANISM OF ACTION:
- Applied to the skin, Progesterone helps balance the effects of estrogen on the body, supporting hormonal equilibrium and providing relief from menopause-related symptoms.
COMMON SIDE EFFECTS:
- Side effects may include skin irritation, dizziness, or mood changes. Long-term use requires monitoring to avoid hormone imbalances.
CONTRAINDICATIONS:
- It is contraindicated in women with hormone-sensitive cancers or severe liver disease. It should not be used during pregnancy.
MORE INFORMATION:
- FDA Data Safety Sheet: Not available for topical use
- Stanczyk FZ, Matharu H, Winer SA. Bioidentical hormones. Climacteric. 2021 Feb;24(1):38-45.
- Leonetti et al. Transdermal progesterone cream as an alternative progestin in hormone therapy. Altern Ther Health Med. 2005 Nov-Dec;11(6):36-8.
- Stanczyk et al. Progestogens used in postmenopausal hormone therapy: differences in their pharmacological properties, intracellular actions, and clinical effects. Endocr Rev. 2013 Apr;34(2):171-208.
- Stanczyk et al. Percutaneous administration of progesterone: blood levels and endometrial protection. Menopause. 2005 Mar;12(2):232-7.
Progesterone Vaginal Suppository
INDICATIONS AND USAGE:
- Intravaginal progesterone is used to treat infertility, support early pregnancy, and in hormone replacement therapy for menopausal women.
ADMINISTRATION ROUTE:
- Vaginal Insert (Suppository)
FORMULATIONS & COST:
- The price sheet below already reflects the 50% HRT member discount.
AMOUNT | COST |
---|---|
100mg insert (#30) | $65 |
100mg insert (#60) | $85 |
200mg insert (#30) | $70 |
200mg insert (#60) | $100 |
MECHANISM OF ACTION:
- Delivered directly to the vaginal mucosa, Progesterone supports the uterine lining, maintaining conditions necessary for embryo implantation and pregnancy. It also balances estrogen therapy in HRT.
COMMON SIDE EFFECTS:
- Side effects may include vaginal irritation, discharge, headaches, or mood swings. It may also cause dizziness.
CONTRAINDICATIONS:
- Contraindications include known hormone-sensitive cancers, unexplained vaginal bleeding, or severe liver disease.
MORE INFORMATION:
- FDA Data Safety Sheet for Progesterone
- Fitzpatrick LA et al. Micronized progesterone: clinical indications and comparison with current treatments. Fertility and Sterility. 1999 Sept;72(3):389-397.
- Graham S et al. Review of menopausal hormone therapy with estradiol and progesterone versus other estrogens and progestins. Gynecological Endocrinology 2022 38(11), 891–910.
GLP-1 Pricing Table
PRICING MODEL:
- Patients pay a $249 monthly provider fee for GLP-1 therapy plus a vial charge when additional meds are needed. One vial charge is paid at sign-up to cover the cost of your initial medication. The first vial will last an average patient approximately three months.
- Refill vial charges vary depending on which medication is selected and how much medication is required. Patients who maximize lifestyle changes (allowing them to use less medication) will require refills less often and pay less! See below for a chart of the “all-in” monthly price for patients at each dosing level.
- For a comprehensive description of each medication and a listing of each medication’s refill options and pricing, visit the Recess Rx homepage and navigate to Medications > GLP-1 Peptides.
Treatment range: 0.5mg-2.5mg per week
DOSE PER WEEK | AVG COST |
---|---|
0.5mg / week | $289/mo |
1.0mg / week | $327/mo |
1.5mg / week | $365/mo |
2.0mg / week | $403/mo |
2.5mg / week | $441/mo |
TIRZEPATIDE COST ESTIMATOR
Treatment range: 3.0mg-15.0mg per week
DOSE PER WEEK | COST (AVG.) |
---|---|
3.0mg / week | $333 |
6.0mg / week | $417 |
9.0mg / week | $501 |
12.0mg / week | $585 |
15.0mg / week | $669 |
HRT Pricing Rubric
- HRT medication subscriptions consist of a $149 monthly fee plus a refill charge each time a medication refill is needed. Many HRT medications need refilled every 2-4 months.
- The total charge will vary depending on the medication regimen selected. We offer a large variety of HRT regimens for both men and women, including direct hormone replacement (via injection, oral capsules and/or troches, topical creams, etc) and alternative regimens that increase body’s natural hormone production (such as clomiphene and kisspeptin-10). HRT members pay the wholesale pharmacy price for HRT medications.
- For a comprehensive, sex-specific description of each HRT medication we offer and a full listing of each medication’s refill options and pricing, visit the Recess Rx homepage and navigate to Medications > HRT Member Meds.
One of my core memories is standing in front of a mirror at 14 and promising I wouldn’t end up like adults I saw trying–and failing–to get down to a healthy weight and stay there.
Well, as it turns out…
Getting and staying healthy and fit in our modern Western world is not so easy! In fact, for most people–even if you know how–it is really, really hard.
Exercising is hard, knowing how-when-and-what-the-heck-can-I-even-eat is hard, getting enough sleep and drinking enough water is hard, saying no to hyper-palatable, endlessly available, addictive junk food and drink is hard, not using drugs or alcohol is hard, “finding the time” is hard, dealing with stress is hard, fighting bad genes, injuries, and pain is hard!
Sometimes it all just feels darn near impossible.
And yet. It IS possible. And it is SO important to try.
As an Emergency Medicine doctor, a good portion of my days are spent in the Emergency Department taking care of people with complications from chronic diseases.
High blood pressure. High cholesterol. Obesity. Diabetes. Coronary Artery Disease. Congestive Heart Failure. Stroke. Emphysema. Cancer. Peripheral Vascular Disease.
Patients who can’t walk, or can’t move, or can’t move, or can’t breathe. Patients who have lost–or are losing–the ability to enjoy their work, their families, and their hobbies. Patients whose every day efforts are spent simply staying alive.
This is the natural end point of our culture, diet, and lifestyle in the United States. These conditions cause immense suffering.
I have dedicated my life to learning how to keep people from getting to that point. The tragedy (and the ray of hope) is that in nearly all cases, these diseases can be prevented! And many times, reversed!
But how?!
It hasn’t been easy for me. I have had many successes and many failures along the way.
I’ve been at <8% body fat as a finely tuned competitive athlete and ballroom and latin dancer. I’ve ALSO been >40% body fat, wearing XXL scrubs as a medical resident working 100+ hours a week, while trying to keep my family life afloat, with exercising and eating healthy entirely absent from my life–and feeling like the challenges were insurmountable.
I’ve struggled through injuries and chronic pain that made exercising feel impossible. I’ve battled binge eating, excessive exercise, and have struggled at times not to succumb to our culture’s over-emphasis of aesthetics over real, sustained, meaningful health.
I’ve had to separate the good from the nonsense when it comes to the endless flood of questionable nutrition and exercise advice. I haven’t done it on my own, either–I’ve needed lots of help along the way.
I now have the wisdom, knowledge, experience, and the plan to help anyone who is willing to get, and stay, healthy and fit.
I combine my expertise with a wide variety of cutting-edge treatments to maximize your health and wellness. At Recess Rx we offer everything from obesity treatments to peptide therapy to hormone replacement therapy, and everything in between. We also always address the root causes of disease and focus on fixing the lifestyle factors that got you in an unhealthy place in the first place.
It might not be easy for you, either. But it can be done. I started Recess Rx to help make the impossible possible for anyone willing to try.
Will you join me? We can do it together!