MOTS-C

PEPTIDES+ MEMBERS ONLY

INDICATIONS FOR USE

MOTS-C is an experimental peptide investigated for its role in mitochondrial function, energy regulation, and metabolic health. It shows promise for age-related metabolic disorders, obesity, and type 2 diabetes.

ROUTE OF ADMINISTRATION

  • Subcutaneous injection.

FORMULATIONS AND PRICING

FormulationPrice
50mg vial (10mg/mL x 5mL)$300

COMMON INITIAL DOSING REGIMENS

  • Research protocols often involve 10–20 mg administered subcutaneously 2–3 times per week for several weeks, followed by rest periods.

  • Suggested protocol: Inject 5mg (50 units via insulin syringe) SQ every 5 days for 20 days; may repeat once every 6 months

MECHANISM OF ACTION

  • MOTS-C is encoded by mitochondrial DNA and regulates metabolic homeostasis by modulating AMPK and insulin sensitivity. It enhances mitochondrial function, promotes glucose uptake, and protects against metabolic stress.

COMMON SIDE EFFECTS

  • Mild: Fatigue, headache, or injection site reactions.

  • Rare: Potential mitochondrial overactivation leading to oxidative stress or tissue fatigue.

CONTRAINDICATIONS

  • Absolute: Hypersensitivity to MOTS-C or its excipients.

  • Relative: Use cautiously in individuals with mitochondrial disorders, as overactivation may exacerbate underlying dysfunction.

MORE INFORMATION

  • FDA Safety Data Sheet not available (experimental peptide).